Stronger diet effect seen in Gleason grade group >6 and in International Society of Urological Pathology grade 3 + 4 + 5 tumors<\/p>\n<\/h3>\n
By Elana Gotkine HealthDay Reporter<\/b><\/p>\n
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WEDNESDAY, April 19, 2023 (HealthDay News) — Adherence to a Western diet may have a detrimental effect on the risk for prostate cancer, according to a study published online April 19 in BJU International<\/em>.<\/p>\n Adela Castell \u00b3, Ph.D., from the University of Alcal \u00a1 in Madrid, and colleagues examined the association between three dietary patterns (Western, Prudent, and Mediterranean) and prostate cancer risk in a study involving 15,296 men recruited during 1992 to 1996. The associations between dietary patterns and prostate cancer risk (global, for Gleason grade groups 6 and >6, and for International Society of Urological Pathology [ISUP] grade 1 + 2 and ISUP grade 3 + 4 + 5) were examined.<\/p>\n The researchers found that for the Prudent and Mediterranean dietary patterns, there was no effect on prostate cancer risk, while there was a suggestion of a detrimental effect of the Western dietary pattern (hazard ratioquartile[Q]4vsQ1<\/sub>, 1.29; 95 percent confidence interval, 0.96 to 1.72). This effect was only seen for Gleason grade group >6 (hazard ratioQ3vsQ1<\/sub>, 1.61; 95 percent confidence interval, 1.00 to 2.59; hazard ratioQ4vsQ1<\/sub>, 1.60; 95 percent confidence interval, 0.96 to 2.67) and was stronger for ISUP grade 3 + 4 + 5 tumors (hazard ratioQ2vsQ1<\/sub>, 1.97; 95 percent confidence interval, 0.98 to 3.93; hazard ratioQ3vsQ1<\/sub>, 2.72; 95 percent confidence interval, 1.35 to 5.51; hazard ratioQ4vsQ1<\/sub>, 2.29; 95 percent confidence interval, 1.07 to 4.92).<\/p>\n “Our results indicate that avoiding unhealthy dietary habits could be the best nutritional strategy to prevent aggressive prostate cancer,” Castell \u00b3 said in a statement.<\/p>\n