Pooled incidence 1.7 and 12.1 per 100 person-years for HIV, hepatitis C, respectively, with higher risk seen in the young and in women<\/p>\n<\/h3>\n
By Elana Gotkine HealthDay Reporter<\/b><\/p>\n
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MONDAY, April 10, 2023 (HealthDay News) — Among people who inject drugs (PWID), the pooled incidences of HIV and hepatitis C virus (HCV) are 1.7 and 12.1 per 100 person-years, respectively, with increased risks in young PWID and in women, according to a review published online March 27 in The Lancet Gastroenterology & Hepatology<\/em>.<\/p>\n Adelina Artenie, Ph.D., from Bristol Medical School at the University of Bristol in the United Kingdom, and colleagues conducted a systematic review and meta-analysis to summarize global data on HIV and primary HCV incidence among PWID and associations with age and gender. A total of 125 records met the inclusion criteria; 64 estimates of HIV incidence and 66 estimates of HCV incidence were identified.<\/p>\n The researchers found that pooled HIV incidence was 1.7 per 100 person-years and pooled HCV incidence was 12.1 per 100 person-years. Compared with older PWID, young PWID had a greater risk for HIV and HCV acquisition (relative risk, 1.5 for both). Compared with men, women had a greater risk for HIV and HCV (relative risks, 1.4 and 1.2, respectively). The median risk for bias score was 6, indicating moderate risk for both HIV and HCV.<\/p>\n “Given the higher risks of HIV and HCV acquisition in young versus older PWID and in women versus men who inject drugs, age-appropriate and gender-appropriate prevention and harm reduction measures are also urgently needed to serve these subgroups at high risk,” the authors write.<\/p>\n Several authors disclosed financial ties to the pharmaceutical industry.<\/p>\n Abstract\/Full Text<\/a><\/p>\n Editorial (subscription or payment may be required)<\/a><\/p>\n <\/i><\/p>\n