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THURSDAY, Aug. 23, 2018 (HealthDay News) — Mean systolic blood pressure is increased with increasing sodium intake only in communities in the highest tertile of sodium intake, according to a study published online Aug. 9 in The Lancet<\/i>.<\/p>\n
Andrew Mente, Ph.D., from McMaster University in Hamilton, Canada, and colleagues performed an analysis of the Prospective Urban Rural Epidemiology study in 18 countries to examine the correlations between community-level mean sodium and potassium intake, cardiovascular disease, and mortality. BP was assessed for 95,767 participants in 369 communities, and cardiovascular outcomes were assessed among 82,544 participants in 255 communities.<\/p>\n
The researchers found that there was an increase in mean systolic BP of 2.86 mmHg per 1 g increase in mean sodium intake; only communities in the highest tertile of sodium intake had positive correlations. Significant deviations from linearity were seen for the correlation between mean sodium intake and major cardiovascular events; this resulted from a significant inverse association in the lowest tertile of sodium intake (change, \u22121 events per 1,000 years; 95 percent confidence interval, \u22122 to \u22120.1), no association in the middle tertile (change, 0.24 events per 1,000 years; 95 percent confidence interval, \u22122.12 to 2.61), and a positive but non-significant association in the highest tertile (change, 0.37 events per 1,000 years; 95 percent confidence interval, \u22120.03 to 0.78). Compared with other countries, in China there was a strong association with stroke (mean sodium intake, 5.58 mg\/day; 0.42 events per 1,000 years).<\/p>\n
“Sodium intake was associated with cardiovascular disease and strokes only in communities where mean intake was greater than 5 g\/day,” the authors write.<\/p>\n
The study was funded in part by pharmaceutical companies.<\/p>\n
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