Higher risk seen for preterm birth, gestational hypertension, and preeclampsia<\/p>\n<\/h3>\n
By Lori Solomon HealthDay Reporter<\/b><\/p>\n
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THURSDAY, Feb. 16, 2023 (HealthDay News) — A history of migraine before pregnancy is associated with a higher risk for adverse outcomes during pregnancy, according to a study published online Jan. 19 in Neurology<\/em>.<\/p>\n Alexandra C. Purdue-Smithe, Ph.D., from Brigham and Women s Hospital in Boston, and colleagues examined associations of self-reported physician-diagnosed migraine with adverse pregnancy outcomes. The analysis included data from 30,555 incident pregnancies among 19,694 participants in the prospective Nurses’ Health Study II (1989 to 2009).<\/p>\n The researchers found that when adjusting for age, adiposity, and other health and behavioral factors, prepregnancy migraine (11 percent) was associated with higher risks for preterm delivery (relative risk [RR], 1.17; 95 percent confidence interval [CI], 1.05 to 1.30), gestational hypertension (RR, 1.28; 95 percent CI, 1.11 to 1.48), and preeclampsia (RR, 1.40; 95 percent CI, 1.19 to 1.65) compared with no migraine. However, migraine was not associated with low birth weight (RR, 0.99; 95 percent CI, 0.85 to 1.16) or gestational diabetes (RR, 1.05; 95 percent CI, 0.91 to 1.22). Preeclampsia risk was somewhat higher among participants with migraine with aura (RR, 1.51; 95 percent CI, 1.22 to 1.88) than among those with migraine without aura (RR, 1.30; 95 percent CI, 1.04 to 1.61) compared with no migraine. But other outcomes were similar, regardless of migraine phenotype. <\/p>\n “Migraine history, and to a lesser extent migraine phenotype, appear to be important considerations in obstetric risk assessment and management,” the authors write.<\/p>\n Abstract\/Full Text (subscription or payment may be required)<\/a><\/p>\n <\/i><\/p>\n