Risk for AUD hospitalization higher compared with sleeve gastrectomy and weight management programs<\/p>\n<\/h3>\n
By Lori Solomon HealthDay Reporter<\/b><\/p>\n
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THURSDAY, Jan. 12, 2023 (HealthDay News) — Roux-en-Y gastric bypass (RYGB) is associated with an increased risk for alcohol use disorder (AUD)-related hospitalizations versus both sleeve gastrectomy and weight management programs, according to a study published online Dec. 14 in JAMA Surgery<\/em>.<\/p>\n Nadim Mahmud, M.D., from the University of Pennsylvania in Philadelphia, and colleagues evaluated the effect of RYGB, sleeve gastrectomy, or gastric banding on subsequent AUD-related hospitalization and all-cause mortality versus referral to the MOVE! weight management program alone. The analysis included 1,854 patients (body mass index \u00e2\u0089\u00a530 kg\/m\u00c2\u00b2) treated at 127 Veterans Health Administration health centers.<\/p>\n The researchers found that accounting for time-updating alcohol use and body mass index, RYGB was associated with an increased risk for AUD-related hospitalization versus MOVE! (hazard ratio [HR], 1.70; 95 percent confidence interval [CI], 1.20 to 2.41; P = 0.003) and versus sleeve gastrectomy (HR, 1.98; 95 percent CI, 1.55 to 2.53; P < 0.001). There was no significant difference observed in AUD-related hospitalization between sleeve gastrectomy and MOVE! (HR, 0.76; 95 percent CI, 0.56 to 1.03; P = 0.08). While RYGB was associated with a lower mortality risk compared with MOVE! (HR, 0.63; 95 percent CI, 0.49 to 0.81; P < 0.001), this association was diminished by increasing alcohol use over time.<\/p>\n “The mortality benefit associated with RYGB was diminished by increased alcohol use, highlighting the importance of careful patient selection and alcohol-related counseling for patients undergoing this procedure,” the authors write.<\/p>\n Abstract\/Full Text (subscription or payment may be required)<\/a><\/p>\n Editorial (subscription or payment may be required)<\/a><\/p>\n <\/i><\/p>\n