Pipes, cigars, e-cigarettes, or marijuana not tied to recurrence risk<\/p>\n<\/h3>\n
By Lori Solomon HealthDay Reporter<\/b><\/p>\n
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FRIDAY, Dec. 9, 2022 (HealthDay News) — Longer duration and more pack-years of cigarette smoking are associated with a higher risk for recurrence of non-muscle-invasive bladder cancer (NMIBC), according to a study published online Nov. 30 in JAMA Network Open<\/em>.<\/p>\n Marilyn L. Kwan, Ph.D., from Kaiser Permanente Northern California in Oakland, and colleagues examined associations of use of tobacco (cigarettes, pipes, and cigars), e-cigarettes, and marijuana with the risk for recurrence and progression of NMIBC. The analysis included 1,472 patients with NMIBC diagnosed from 2015 to 2019 and followed for 26.4 months.<\/p>\n The researchers found that longer cigarette smoking duration and more pack-years were associated with a higher risk for recurrence in a dose-dependent manner, with the highest risks for patients who had smoked for \u00e2\u0089\u00a540 years (hazard ratio, 2.36) or \u00e2\u0089\u00a540 pack-years (hazard ratio, 1.97). Recurrence risk was not associated with having ever smoked, being a former or current cigarette smoker, and years since quitting smoking. Furthermore, there were no associations observed for pipes, cigars, e-cigarettes, or marijuana. Just over half of 102 patients offered a smoking cessation intervention (53.8 percent) received an intervention after diagnosis. Female patients were more likely than male patients to participate in such interventions (76.7 versus 44.7 percent).<\/p>\n “Cigarette smoking remains a critical exposure before and after diagnosis in survivors of NMIBC,” the authors write.<\/p>\n