No influence seen on height for age, BMI for age, waist-to-height ratio, percentage body fat, fat mass, fat-free mass, or Tanner scores<\/p>\n<\/h3>\n
By Elana Gotkine HealthDay Reporter<\/b><\/p>\n
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MONDAY, Nov. 28, 2022 (HealthDay News) — For children with a high prevalence of vitamin D deficiency (25-hydroxyvitamin D [25(OH)D] <20 ng\/mL), vitamin D3<\/sub> supplementation increases 25(OH)D concentrations but does not influence growth, body composition, or pubertal development, according to a study published online Nov. 28 in JAMA Pediatrics<\/em>.<\/p>\n Davaasambuu Ganmaa, Ph.D., from the Harvard T. H. Chan School of Public Health in Boston, and colleagues conducted a secondary analysis of a double-blind, placebo-controlled randomized clinical trial, conducted among school-aged children in Mongolia from June 2016 to June 2019. A total of 8,851 children were included in the study and were randomly assigned to receive weekly oral doses of vitamin D3<\/sub> at 14,000 IU or placebo for three years (4,418 and 4,433 children, respectively).<\/p>\n Of the participants, 95.5 percent were vitamin D-deficient at baseline; the mean end-of-study 25(OH)D concentrations were 31.0 and 10.7 ng\/mL for those randomly assigned to vitamin D and placebo, respectively. The researchers found that vitamin D supplementation had no influence on mean height for age, body mass index for age, waist-to-height ratio, percentage body fat, fat mass, fat-free mass, or Tanner scores overall or within subgroups defined according to baseline 25(OH)D concentrations, estimated calcium intake, or sex.<\/p>\n “This intervention did not influence growth, body composition, or pubertal development, either in the study population as a whole or within subgroups having the lowest baseline 25(OH)D concentrations or calcium intake values,” the authors write.<\/p>\n Several authors disclosed financial ties to the pharmaceutical industry.<\/p>\n Abstract\/Full Text (subscription or payment may be required)<\/a><\/p>\n <\/i><\/p>\n