Significant increases seen among youngest-aged men and women, even during omicron surge<\/p>\n<\/h3>\n
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WEDNESDAY, Oct. 26, 2022 (HealthDay News) — Excess acute myocardial infarction (AMI)-associated mortality seen during the COVID-19 pandemic persisted through the omicron surge and was most pronounced in younger-aged adults, according to a study published online Sept. 29 in the Journal of Medical Virology<\/em>.<\/p>\n Yee Hui Yeo, M.D., from Cedars-Sinai Medical Center in Los Angeles, and colleagues examined the extent and disparity in excess AMI-associated mortality during the pandemic. A total of 1,522,669 AMI-associated deaths occurring between April 1, 2012, and March 31, 2022, were identified. The age-standardized mortality rate for AMI-associated deaths was compared between the prepandemic and pandemic periods.<\/p>\n The researchers found that AMI-associated mortality rates decreased across all subgroups before the pandemic. During the pandemic, these trends reversed, with significant increases seen for the youngest-aged men and women, even during the omicron surge (October 2021 to March 2022). In the youngest and middle-age group, the semiannual percentage change in AMI-associated mortality increased by 5.3 and 3.4 percent, respectively. Excess mortality was most pronounced for the youngest-aged decedents (25 to 44 years), ranging from 23 to 34 percent compared with 13 to 18 percent for the oldest age groups.<\/p>\n “There are several potential explanations for the rapid rise in cardiac deaths in patients with COVID-19, yet still many unanswered questions,” Yeo said in a statement. “Importantly, our results highlight disparities in mortality that have emerged from the COVID-19 pandemic and that are persisting even through the omicron era.”<\/p>\n Two authors disclosed financial ties to the pharmaceutical industry.<\/p>\n Abstract\/Full Text (subscription or payment may be required)<\/a><\/p>\n <\/i><\/p>\n