{"id":90725,"date":"2022-10-27T00:00:00","date_gmt":"2022-10-27T00:00:00","guid":{"rendered":"http:\/\/medgoo.com\/index.php\/2022\/10\/27\/breathing-trials-compared-for-patients-at-risk-for-extubation-failure\/"},"modified":"2022-10-28T22:21:51","modified_gmt":"2022-10-28T22:21:51","slug":"breathing-trials-compared-for-patients-at-risk-for-extubation-failure","status":"publish","type":"post","link":"https:\/\/medgoo.com\/index.php\/2022\/10\/27\/breathing-trials-compared-for-patients-at-risk-for-extubation-failure\/","title":{"rendered":"Breathing Trials Compared for Patients at Risk for Extubation Failure"},"content":{"rendered":"<h3>\n<p>No difference seen in number of ventilator-free days, time to extubation, reintubation with PSV versus T-piece<\/p>\n<\/h3>\n<p><b><\/b><\/p>\n<p><b><\/b><\/p>\n<p>THURSDAY, Oct. 27, 2022 (HealthDay News) &#8212; For patients at high risk for extubation failure, the number of ventilator-free days at day 28 is no different for spontaneous-breathing trials performed with use of pressure-support ventilation (PSV) or a T-piece, according to a study published online Oct. 26 in the <em>New England Journal of Medicine<\/em> to coincide with LIVES 2022, the annual congress of the European Society of Intensive Care Medicine, held from Oct. 22 to 26 in Paris.<\/p>\n<p>Arnaud W. Thille, M.D., Ph.D., from Centre Hospitalier Universitaire de Poitiers in France, and colleagues randomly assigned patients with a high risk for extubation failure to undergo spontaneous-breathing trials performed with use of PSV or a T-piece. The analysis included 969 patients (484 in the PSV group and 485 in the T-piece group).<\/p>\n<p>The researchers found that the median number of ventilator-free days was 27 in both the PSV and T-piece groups at day 28. Extubation was performed within 24 hours in 77.7 and 72.2 percent of patients in the PSV and T-piece groups, respectively; extubation was performed within seven days in 97.7 and 94.4 percent of patients, respectively. Reintubation was performed in 14.9 and 13.6 percent of patients in the PSV and T-piece groups, respectively. In nine patients (three in the PSV group and six in the T-piece group), cardiac or respiratory arrest was a reason for reintubation.<\/p>\n<p>&#8220;Our primary analysis showed no significant difference between these two strategies with respect to the number of ventilator-free days after the initial spontaneous-breathing trial,&#8221; the authors write.<\/p>\n<p><a href=\"https:\/\/www.nejm.org\/doi\/full\/10.1056\/NEJMoa2209041\" target=\"_blank\" rel=\"noopener\">Abstract\/Full Text (subscription or payment may be required)<\/a><\/p>\n<p><a href=\"https:\/\/www.nejm.org\/doi\/full\/10.1056\/NEJMe2212594\" target=\"_blank\" rel=\"noopener\">Editorial (subscription or payment maybe required)<\/a><\/p>\n<p><a href=\"https:\/\/lives2022.e-lives.org\/\" target=\"_blank\" rel=\"noopener\">More Information<\/a><\/p>\n<p><i><\/i><\/p>\n<p><i>Copyright \u00a9 2022 <a href=\"https:\/\/www.healthday.com\/\" target=\"_new\" rel=\"noopener\">HealthDay<\/a>. All rights reserved.<\/i><\/p>\n","protected":false},"excerpt":{"rendered":"<p>No difference seen in number of ventilator-free days, time to extubation, reintubation with PSV versus T-piece<\/p>\n","protected":false},"author":6,"featured_media":90814,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[6],"tags":[11],"class_list":["post-90725","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news","tag-news"],"_links":{"self":[{"href":"https:\/\/medgoo.com\/index.php\/wp-json\/wp\/v2\/posts\/90725","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medgoo.com\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/medgoo.com\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/medgoo.com\/index.php\/wp-json\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"https:\/\/medgoo.com\/index.php\/wp-json\/wp\/v2\/comments?post=90725"}],"version-history":[{"count":1,"href":"https:\/\/medgoo.com\/index.php\/wp-json\/wp\/v2\/posts\/90725\/revisions"}],"predecessor-version":[{"id":90813,"href":"https:\/\/medgoo.com\/index.php\/wp-json\/wp\/v2\/posts\/90725\/revisions\/90813"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medgoo.com\/index.php\/wp-json\/wp\/v2\/media\/90814"}],"wp:attachment":[{"href":"https:\/\/medgoo.com\/index.php\/wp-json\/wp\/v2\/media?parent=90725"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/medgoo.com\/index.php\/wp-json\/wp\/v2\/categories?post=90725"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/medgoo.com\/index.php\/wp-json\/wp\/v2\/tags?post=90725"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}