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MONDAY, Aug. 6, 2018 (HealthDay News) — The combination of digital mammography (DM) and digital breast tomosynthesis (DBT) detects 90 percent more breast cancers than digital mammography alone, according to a study published in the August issue of Radiology<\/i>.<\/p>\n
Pierpaolo Pattacini, M.D., from AUSL Reggio Emilia in Italy, and colleagues compared DM to DBT+DM for breast cancer screening as part of the Reggio Emilia Tomosynthesis trial. In this trial, eligible women (aged 45 to 70 years old) were randomized (1:1) to either DM+DBT (9,777 patients) or DM alone (9,783 patients). Both involved two projections and double readings.<\/p>\n
The researchers found that detection was 4.5 per 1,000 in the DM arm and 8.6 per 1,000 in the DM+DBT arm. Recall rates were similar in both arms. The positive predictive value of the recall was 13.0 and 24.1 percent, respectively (P = 0.0002), with 72 of 80 cancers in the DBT+DM arm positive for at least one DBT-alone reading. Detection rate using DM+DBT was stronger for ductal carcinoma in situ. It was also notable for small and medium invasive cancers, but not for large ones.<\/p>\n
“Tomosynthesis and digital mammography is much more sensitive than digital mammography,” Pattacini said in a statement. “The vast majority of the advantage is due to tomosynthesis alone.”<\/p>\n
Several authors report financial ties to medical device companies, including GE Healthcare, which provided the equipment for the study.<\/p>\n
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