Patients with preclinical heart failure and uncontrolled diabetes have increased risk for progression of heart failure <\/p>\n<\/h3>\n
<\/b><\/p>\n
<\/b><\/p>\n
WEDNESDAY, June 22, 2022 (HealthDay News) — Among older adults with stage B preclinical heart failure, uncontrolled diabetes is associated with a substantial risk for heart failure progression, according to a study published online in the June 14 issue of the Journal of the<\/em> American College of Cardiology<\/em>.<\/p>\n Justin B. Echouffo-Tcheugui, M.D., Ph.D., from Johns Hopkins University in Baltimore, and colleagues examined the influence of diabetes on the progression from preclinical heart failure stages (A or B based on the 2021 Universal Definition) to overt heart failure. The analysis included 4,774 adults with preclinical heart failure (2011 to 2013).<\/p>\n The researchers found that during 8.6 years of follow-up, stage B participants with hemoglobin A1C (HbA1c) \u00e2\u0089\u00a57 percent experienced clinical heart failure at a younger age versus those with controlled diabetes or without diabetes. Compared with stage A (hazard ratio, 1.52; 95 percent confidence interval, 0.53 to 4.38), HbA1c \u00e2\u0089\u00a57 percent was more strongly associated with heart failure in stage B (hazard ratio, 1.83; 95 percent confidence interval, 1.33 to 2.51). Similarly, participants with stage B and HbA1c \u00e2\u0089\u00a57 percent had an increased risk for heart failure progression versus patients with stage A without diabetes (hazard ratio, 7.56; 95 percent confidence interval, 4.68 to 12.20).<\/p>\n “We know that diabetes and heart failure are highly prevalent and strongly interrelated,” Echouffo Tcheugui said in a statement. “But as far as we know, this is the first study to assess their relationship through this specific lens. We want to continue exploring that relationship.”<\/p>\n Several authors disclosed financial ties to medical and pharmaceutical companies. <\/p>\n Abstract\/Full Text (subscription or payment may be required)<\/a><\/p>\n <\/a>Editorial (subscription or payment may be required)<\/a><\/p>\n <\/i><\/p>\n