Increased risk seen using frequentist approach and Bayesian approach; significant association also seen in subgroup analyses<\/p>\n<\/h3>\n
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TUESDAY, June 14, 2022 (HealthDay News) — For men, smoking is associated with increased fracture risk, according to a meta-analysis published online June 3 in Scientific Reports.<\/em><\/p>\n Yingke Xu, M.P.H., from the University of Nevada in Las Vegas, and colleagues examined the association between smoking and fracture risk in men in a meta-analysis of data from 27 studies that met the inclusion criteria.<\/p>\n The researchers found that smoking was associated with a significantly increased risk of fracture in the frequentist approach and the Bayesian approach (relative risks, 1.37 and 1.36, respectively). There was significant heterogeneity noted in the meta-analysis (Higgin’s I, 83 percent). In prespecified sensitivity and subgroup analyses, a significant association was also observed. Results were similar in the groups containing a large sample size (\u00e2\u0089\u00a510,000 participants) and a small sample size (<10,000 participants); the pooled relative risks were 1.23 and 1.56, respectively. With the Bayesian method, the effect sizes were 1.23 and 1.57 for the large and small sample size groups, respectively.<\/p>\n “Our results have crucial implications in public health, with the most apparent being that quitting smoking can reduce an individual s risk of bone fracture, both now and later in life,” the authors write.<\/p>\n