Study in Ethiopia shows risk factors for peptic ulcer disease include H. pylori<\/em> infection and NSAID\/acetylsalicylic acid use<\/p>\n<\/h3>\n <\/b><\/p>\n <\/b><\/p>\n TUESDAY, May 24, 2022 (HealthDay News) — In Northwest Ethiopia, 35 percent of patients with dyspepsia have peptic ulcer disease, with risk factors including Helicobacter pylori <\/em>(H. pylori<\/em>) infection and nonsteroidal anti-inflammatory drug (NSAID)\/acetylsalicylic acid (ASA) use, according to a study published online April 5 in BMC Gastroenterology<\/em>.<\/p>\n Belete Assefa, from the University of Gondar in Ethiopia, and colleagues conducted an institutional-based cross-sectional study involving 218 dyspeptic patients who underwent upper gastrointestinal endoscopic evaluations to determine the magnitude and associated factors of peptic ulcer disease. Clinical information was obtained using a semistructured questionnaire.<\/p>\n The researchers found that 49 percent of the patients had active H. pylori<\/em> infection. In 35 percent of patients with dyspepsia, peptic ulcer disease was diagnosed. Risk factors for peptic ulcer disease included H. pylori<\/em> infection and NSAID\/ASA use (adjusted odds ratios, 6.298 and 6.252, respectively).<\/p>\n “Medical treatment of peptic ulcer disease should target treatment of H. pylori<\/em> infection and cautious use of NSAIDs\/ASA,” the authors write. “Community-based study is required to conclude the actual findings in the target population.”<\/p>\n