Reduced incidence of mobility disability seen in older adults with physical frailty and sarcopenia receiving multicomponent intervention<\/p>\n<\/h3>\n
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FRIDAY, May 13, 2022 (HealthDay News) — Among older adults with physical frailty and sarcopenia and a short physical performance battery (SPPB) score of 3 to 7, the incidence of mobility disability is reduced with participation in a multicomponent intervention, according to a study published online May 11 in The BMJ<\/em>.<\/p>\n Roberto Bernabei, M.D., from Fondazione Policlinico Universitario “Agostino Gemelli” in Rome, and colleagues conducted a randomized controlled trial at 16 clinical sites across 11 European countries involving 1,519 community-dwelling men and women aged 70 years or older with physical frailty and sarcopenia, defined as having an SPPB score of 3 to 9 points, low appendicular lean mass, and the absence of mobility disability. Participants were randomly assigned to receive a multicomponent intervention or education on healthy aging (control; 760 and 759 participants, respectively).<\/p>\n The researchers found that among participants with SPPB scores of 3 to 7, mobility disability occurred in 46.8 and 52.7 percent of those assigned to the intervention and control groups, respectively (hazard ratio, 0.78; 95 percent confidence interval, 0.67 to 0.92; P = 0.005). Persistent mobility disability occurred in 21 and 25 percent of participants in the intervention and control groups, respectively (hazard ratio, 0.79; 95 percent confidence interval, 0.62 to 1.01; P = 0.06). At 24 and 36 months, the between-group difference in the SPPB score was 0.8 points and 1.0 point, respectively, in favor of the multicomponent intervention.<\/p>\n “A multicomponent intervention based on physical activity with technological support and nutritional counselling was associated with a reduction in the incidence of mobility disability,” the authors write.<\/p>\n Several authors disclosed financial ties to the pharmaceutical industry.<\/p>\n Abstract\/Full Text<\/a><\/p>\n