Patients with clinical hypothyroidism and a high prehospitalization TSH level had longer length of stay, increased risk for readmission<\/p>\n<\/h3>\n
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THURSDAY, April 28, 2022 (HealthDay News) — Suboptimal treatment of hypothyroidism is associated with worse hospital outcomes, according to a study published online April 26 in the Journal of Clinical Endocrinology & Metabolism<\/em>.<\/p>\n Matthew D. Ettelson, M.D., from the University of Chicago, and colleagues conducted a retrospective cohort study to identify differences in hospital outcomes between patients with and without hypothyroidism using data from a U.S.-based commercial claims database from Jan. 1, 2008, to Dec. 31, 2015. Participants were aged 64 years and younger and had a thyrotropin (TSH) level collected prior to hospital admission. Patients with hypothyroidism were classified into four subgroups according to prehospitalization TSH level.<\/p>\n The final study population included 43,478 patients, of whom 8,873 had a diagnosis of hypothyroidism. The researchers found that patients with a high prehospitalization TSH level (TSH >10.00 mIU\/L) had a length of stay that was 1.2 days longer and had an increased risk for 30- and 90-day readmission compared with balanced controls (relative risks, 1.49 and 1.43, respectively). Reduced risks for in-hospital mortality and 90-day readmission were seen for patients with normal TSH levels (relative risks, 0.46 and 0.92, respectively).<\/p>\n “It is important for both patients and physicians to know that maintaining optimal thyroid hormone replacement is important to minimize length of hospital stays and hospital readmission,” Ettelson said in a statement. “It is particularly important for planned admissions where thyroid hormone replacement can be adjusted if needed prior to admission.”<\/p>\n One author disclosed financial ties to the pharmaceutical industry.<\/p>\n Abstract\/Full Text (subscription or payment may be required)<\/a><\/p>\n <\/i><\/p>\n