Sufficient circulating vitamin D concentration linked to lower risk for breast cancer in Hispanic\/Latina women<\/p>\n<\/h3>\n
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MONDAY, April 25, 2022 (HealthDay News) — Sufficient circulating concentrations of vitamin D may protect against breast cancer in Hispanic\/Latina women, according to a study published online April 25 in Cancer<\/em>.<\/p>\n Katie M. O Brien, Ph.D., from the National Institute of Environmental Health Sciences in Research Triangle Park, North Carolina, and colleagues examined the association between vitamin D levels and breast cancer among 290 Black\/African American and 125 non-Black Hispanic\/Latina women participating in the national Sister Study cohort.<\/p>\n The researchers found that during a mean follow-up of 9.2 years, women with circulating 25-hydroxyvitamin D (25[OH]D) concentrations above the clinical cut point for deficiency (>20.0 ng\/mL) had lower breast cancer rates than women with concentrations \u00e2\u0089\u00a420 ng\/mL (hazard ratio, 0.79; 95 percent confidence interval, 0.61 to 1.02). Among Hispanic\/Latina women, the inverse association was stronger (hazard ratio, 0.52; 95 percent confidence interval, 0.29 to 0.93), and the association was weaker among Black\/African American women (hazard ratio, 0.89; 95 percent confidence interval, 0.68 to 1.18; P for heterogeneity = 0.13). Results did not differ by menopausal status, follow-up time, estrogen receptor status, or invasiveness. There was no independent association seen between either 24,25(OH)\u00e2\u0082\u0082D or the 24,25(OH)\u00e2\u0082\u0082D-to-25(OH)D ratio and breast cancer risk.<\/p>\n “Because women who identify as members of these groups have lower vitamin D levels, on average, than non-Hispanic White women, they could potentially receive enhanced health benefits from interventions promoting vitamin D intake,” O’Brien said in a statement. “However, questions remain about whether these associations are truly causal and, if so, what levels of vitamin D are most beneficial.”<\/p>\n Abstract\/Full Text (subscription or payment may be required)<\/a><\/p>\n <\/i><\/p>\n