Alterations seen in basal heart rate, heart rate response to physical activity, circadian variation in heart rate, autocorrelation of heart rate<\/p>\n<\/h3>\n
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FRIDAY, April 22, 2022 (HealthDay News) — There are alterations in physiologically based parameters of heart rate around the time of COVID-19 symptom onset, which can differentiate symptomatic and healthy periods, according to a study published in the April 19 issue of Cell Reports Medicine<\/em>.<\/p>\n Caleb Mayer, from the University of Michigan in Ann Arbor, and colleagues adapted a validated algorithm, developed to estimate daily circadian phase from wearable heart rate and step data. The algorithm estimates six total parameters; these parameters were estimated each day the patient had wearable heart rate data. A dynamic profile of the parameters was recovered for each individual, before and after COVID-19 infection.<\/p>\n The researchers observed significant alterations in the separate physiological features of basal heart rate, heart rate response to physical activity, circadian variation in heart rate, and autocorrelation of heart rate; these could differentiate symptomatic versus healthy periods. At symptom onset, increased heart rate and autocorrelation began, while the heart rate response to activity increased shortly after onset of symptoms, with a greater increase for individuals with cough. Symptom onset was associated with blunting of circadian variation in heart rate, indicated by uncertainty in the phase estimate.<\/p>\n “Identifying the varying patterns of different heart rate parameters derived from wearables across the course of COVID-19 infection is a substantial advance for the field,” a coauthor said in a statement. “This work can help us more meaningfully follow populations in future COVID-19 waves.”<\/p>\n Several authors disclosed financial ties to Arcascope, which makes circadian rhythms software, but did not sponsor the study. Several authors are inventors of intellectual property related to this study.<\/p>\n