Micro-mechanical system using vibration motor and camera on smartphones can compute the PT\/INR<\/p>\n<\/h3>\n
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MONDAY, Feb. 14, 2022 (HealthDay News) — A micro-mechanical clot detection system using the vibration motor and camera on smartphones correlates strongly with laboratory and point-of-care prothrombin time (PT)\/international normalized ratio (INR) testing for plasma and whole blood, according to a study published online Feb. 11 in Nature Communications<\/em>.<\/p>\n Justin Chan, from the Paul G. Allen School of Computer Science and Engineering at the University of Washington in Seattle, and colleagues report on a proof-of-concept PT\/INR testing system that makes use of the vibration motor and camera on smartphones to track micro-mechanical movements of a copper particle. Using 140 anonymized plasma samples, PT\/INR computed by the smartphone system was compared with laboratory values.<\/p>\n The researchers found that the inter-class correlation coefficients were 0.963 and 0.966, which was within the accuracy range for commercial point-of-care testing coagulometers. Performance was similar on 80 anonymized samples of whole blood using a single drop of blood (10 \u00c2\u00b5l). The smartphone system demonstrated a correlation of 0.974 for both PT\/INR when tested with 79 blood samples with coagulopathic conditions.<\/p>\n “Almost every smartphone from the past decade has a vibration motor and a camera. This means that almost everyone who has a phone can use this. All you need is a simple plastic attachment, no additional electronics of any kind,” a coauthor said in a statement. “This is the best of all worlds — it’s basically the holy grail of PT\/INR testing. It makes it frugal and accessible to millions of people, even where resources are very limited.”<\/p>\n Several authors are listed as inventors on the provisional patent application in the process of being submitted by the University of Washington.<\/p>\n