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TUESDAY, June 19, 2018 (HealthDay News) — Recent-onset diabetes is associated with more than a two-fold greater increase in risk of pancreatic cancer (PC) than long-standing diabetes in African-Americans and Latinos, according to a study published online June 18 in the Journal of the National Cancer Institute<\/i>.<\/p>\n
Veronica Wendy Setiawan, Ph.D., from the University of Southern California in Los Angeles, and colleagues examined the relationships between recent-onset diabetes and PC incidence in 48,995 African-Americans and Latinos in the Multiethnic Cohort (baseline 1993 to 1996).<\/p>\n
The researchers found that 32.3 percent of participants developed diabetes between baseline and 2013, and 408 incident PC cases were identified during follow-up. Diabetes was associated with PC (hazard ratio [HR] at age 75 years, 2.39). For individuals with onset of diabetes within three years of PC diagnosis, there was greater risk compared with those with long-term diabetes across all ages. At age 75 years, the HR for recent-onset diabetes was 4.08 in Latinos and 3.38 in African-Americans.<\/p>\n
“Our findings support the hypothesis that recent-onset diabetes is a manifestation of PC and that long-standing diabetes is a risk factor for this malignancy,” the authors write.<\/p>\n
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