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FRIDAY, June 15, 2018 (HealthDay News) — Between 1999 and 2012, Acinetobacter baumannii<\/i> (A. baumannii<\/i>) antibiotic resistance increased in children, though there was a decreasing trend after 2008, according to a study published in the Journal of the Pediatric Infectious Diseases Society<\/i>.<\/p>\n
Latania K. Logan, M.D., from the Rush University Medical Center in Chicago, and colleagues used antimicrobial susceptibility data from The Surveillance Network to phenotypically identify antibiotic resistance in A. baumannii<\/i> isolates in children aged 1 to 17 years between January 1999 and July 2012. Overall, 6,246 pediatric A. baumannii<\/i> isolates were identified.<\/p>\n
The researchers found that the crude proportion of cephalosporin-resistant (CephR) A. baumannii<\/i> increased from 13.2 percent in 1999 to 23.4 percent in 2012, with a peak of 32.5 percent in 2008. Similarly, the proportion of carbapenem(CR)-resistant A. baumannii<\/i> increased from 0.6 percent in 1999 to 6.1 percent in 2012, peaking at 12.7 percent in 2008. From 1999 to 2012, the proportion of CephR- and CR-resistant A. baumannii<\/i> increased each year by 3 and 8 percent, respectively (CephR odds ratio [OR], 1.03; CR OR, 1.08). After 2008 there was a significant decreasing trend (CephR OR, 0.78; CR OR, 0.73), although resistance remained higher than the 1999 baseline.<\/p>\n
“There is a need for ongoing surveillance of A. baumannii<\/i> infections and continued assessment of effective prevention strategies in vulnerable populations,” the authors write.<\/p>\n
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