Composite neonatal adverse outcome incidence increased from healthy to asymptomatic to symptomatic women<\/p>\n<\/h3>\n
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TUESDAY, Oct. 12, 2021 (HealthDay News) — COVID-19-positive parturients have increased odds of composite adverse neonatal outcomes and overall adverse outcomes, according to a study published online Oct. 10 in the Journal of Maternal-Fetal & Neonatal Medicine<\/em>.<\/p>\n Linda Harel, M.D., from Tel Aviv University in Israel, and colleagues conducted a retrospective cohort study of parturients diagnosed with COVID-19 between March 26 and Sept. 30, 2020. Maternal and neonatal outcomes were examined by comparing COVID-19-negative, asymptomatic COVID-19, and symptomatic COVID-19 parturients.<\/p>\n Overall, 2,299 COVID-19 negative and 172 COVID-19-positive parturients delivered during the study period. The researchers found that gestational diabetes mellitus occurred less often in COVID-19-negative versus COVID-19-positive parturients. Women who were COVID-19-positive had no significant increase in cesarean delivery; there was no significant between-group difference seen in the incidence of preterm deliveries. Only one of 172 COVID-19-positive cases needed mechanical ventilation; there were no maternal deaths. No cases of severe neonatal asphyxia or neonatal death occurred. Composite maternal adverse outcomes showed a trend toward increasing incidence in COVID-19-positive women, with increasing incidence from healthy to asymptomatic to symptomatic women (11.3 to 13.8 to 19.6 percent, respectively). Comparing COVID-19-positive to COVID-19-negative parturients, the adjusted odds ratio for composite neonatal adverse outcomes was 2.1, with corresponding increasing incidence (3.5 to 6.0 to 8.9 percent, respectively); for overall composite adverse outcomes, the adjusted odds ratio was 1.6, with corresponding increasing incidence (13 to 16.4 to 25 percent, respectively).<\/p>\n “Our findings support the importance of vaccinating all pregnant women at all stages of pregnancy,” a coauthor said in a statement.<\/p>\n