No differences seen in mortality, stroke, or other complications for low-risk patients undergoing bicuspid versus tricuspid aortic stenosis<\/p>\n<\/h3>\n
<\/b><\/p>\n
<\/b><\/p>\n
WEDNESDAY, Sept. 29, 2021 (HealthDay News) — Transcatheter aortic valve replacement (TAVR) may be an option for some low-risk patients with bicuspid aortic stenosis, according to a study published in the Sept. 21 issue of the Journal of the American Medical Association<\/em>.<\/p>\n Raj R. Makkar, M.D., from the Cedars-Sinai Medical Center in Los Angeles, and colleagues compared the outcomes of TAVR with a balloon-expandable valve for bicuspid versus tricuspid aortic stenosis. The analysis included 3,168 propensity-matched pairs of patients at low surgical risk undergoing TAVR for bicuspid versus tricuspid aortic stenosis.<\/p>\n The researchers observed no significant difference between the bicuspid and tricuspid groups for rates of death at 30 days (0.9 versus 0.8 percent; hazard ratio [HR], 1.18; 95 percent confidence interval [CI], 0.68 to 2.03; P = 0.55) or at one year (4.6 versus 6.6 percent; HR, 0.75; 95 percent CI, 0.55 to 1.02; P = 0.06). Findings were similar for stroke at 30 days (1.4 versus 1.2 percent; HR, 1.14; 95 percent CI, 0.73 to 1.78; P = 0.55) and at one year (2.0 versus 2.1 percent; HR, 1.03; 95 percent CI, 0.69 to 1.53; P = 0.89). No significant differences were seen between the groups for procedural complications, valve hemodynamics, or moderate or severe paravalvular leak.<\/p>\n “Our hope is for this data to translate into better advocacy and decision-making among healthcare providers and patients diagnosed with bicuspid aortic stenosis,” Makkar said in a statement. “By carefully selecting low-risk surgical patients with bicuspid aortic stenosis, we can add years to life and life to years.”<\/p>\n Several authors disclosed financial ties to the medical device and technology industries.<\/p>\n Abstract\/Full Text (subscription or payment may be required)<\/a><\/p>\n Editorial (subscription or payment may be required) <\/a><\/p>\n <\/i><\/p>\n