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WEDNESDAY, June 6, 2018 (HealthDay News) — Compared to saphenous-vein grafts, radial-artery grafts are associated with a lower rate of adverse cardiac events at five-year follow-up in coronary-artery bypass grafting (CABG) patients, according to research published in the May 31 issue of the New England Journal of Medicine<\/i>.<\/p>\n
Mario Gaudino, M.D., from Weill Cornell Medicine in New York City, and colleagues performed a patient-level combined analysis of six randomized, controlled trials to compare radial-artery grafts (534 patients) and saphenous-vein grafts (502 patients) for CABG.<\/p>\n
The researchers found that over a mean 60 months of follow-up, the incidence of adverse cardiac events was significantly lower with radial-artery grafts versus with saphenous-vein grafts (hazard ratio [HR], 0.67; 95 percent confidence interval [CI], 0.49 to 0.90; P = 0.01). The use of radial-artery grafts was also associated with a significantly lower risk of occlusion (HR, 0.44; 95 percent CI, 0.28 to 0.70; P < 0.001) at follow-up angiography. There was a nominally lower incidence of myocardial infarction (HR, 0.72; 95 percent CI, 0.53 to 0.99; P = 0.04) and a lower incidence of repeat revascularization (HR, 0.50; 95 percent CI, 0.40 to 0.63; P < 0.001) but not a lower incidence of all-cause death (HR, 0.90; 95 percent CI, 0.59 to 1.41; P = 0.68) with the use of radial-artery grafts versus saphenous-vein grafts.<\/p>\n
“As compared with the use of saphenous-vein grafts, the use of radial-artery grafts for CABG resulted in a lower rate of adverse cardiac events and a higher rate of patency at five years of follow-up,” the authors write.<\/p>\n
Several authors disclosed financial ties to the pharmaceutical and medical device industries.<\/p>\n
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