Review finds no beneficial effects on muscle function, strength, or mass<\/p>\n<\/h3>\n
<\/b><\/p>\n
<\/b><\/p>\n
MONDAY, Aug. 30, 2021 (HealthDay News) — Vitamin D supplementation does not show a benefit to muscle health, according to a review published online Aug. 17 in the Journal of Bone and Mineral Research<\/em>.<\/p>\n Lise Sofie Bislev, M.D., Ph.D., from the Aarhus University Hospital in Denmark, and colleagues conducted a systematic literature review to identify studies investigating the effects of vitamin D supplementation versus placebo on muscle health. <\/p>\n Based upon 54 randomized controlled trials (including 8,747 individuals), the researchers found that vitamin D was associated with a significantly longer time spent performing the timed up and go test versus placebo (19 studies, I2<\/sup> = 0 percent). Vitamin D was also associated with a significant lower maximum knee flexion strength (12 studies, I2<\/sup> = 0 percent). In response to vitamin D, the Short Physical Performance Battery showed a tendency toward worsening versus placebo (eight studies). No other measures of muscle health showed between-group differences. <\/p>\n “Care should be taken recommending vitamin D supplementation to improve muscle strength and function in people with normal or only slightly impaired vitamin D status,” Bislev said in a statement. “<\/span>We need to study further whether it may benefit muscles in those with severe vitamin D deficiency, however.”<\/p>\n Abstract\/Full Text (subscription or payment may be required)<\/a><\/p>\n <\/i><\/p>\n