Dose-response relationship seen; most of the risk reduction occurred between 0 and 20 metabolic equivalent hours\/week<\/p>\n<\/h3>\n
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THURSDAY, Aug. 12, 2021 (HealthDay News) — Physical activity is associated with lower all-cause mortality among individuals with prior stroke, with a dose-response relationship, according to a study published online Aug. 11 in Neurology<\/em>.<\/p>\n Raed A. Joundi, M.D., D.Phil., from the Cumming School of Medicine at the University of Calgary in Alberta, Canada, and colleagues examined the correlation between physical activity and all-cause mortality in a cohort of 895 individuals with prior stroke and 97,805 controls, while adjusting for sociodemographic factors, comorbidities, and functional health limitations.<\/p>\n The researchers found that for both those with prior stroke and controls, adherence to physical activity guidelines correlated with a lower risk for death (adjusted hazard ratios, 0.46 [95 percent confidence interval, 0.29 to 0.73] and 0.69 [95 percent confidence interval, 0.62 to 0.76], respectively). A strong dose-response relationship was seen in both groups, with a steep early slope; most of the associated risk reduction occurred between 0 and 20 metabolic equivalent hours\/week. Physical activity was associated with a greater risk reduction in those aged younger than 75 years (adjusted hazard ratio, 0.21; 95 percent confidence interval, 0.10 to 0.43) compared with those aged 75 years or older (adjusted hazard ratio, 0.68; 95 percent confidence interval, 0.42 to 1.12) in the group of stroke survivors.<\/p>\n “Our results are exciting, because just three to four hours a week of walking was associated with big reductions in mortality, and that may be attainable for many community members with prior stroke,” Joundi said in a statement.<\/p>\n One author disclosed financial ties to the biopharmaceutical and medical technology industries.<\/p>\n Abstract\/Full Text (subscription or payment may be required)<\/a><\/p>\n <\/i><\/p>\n