No improvement in symptom severity or quality of life seen with vitamin D supplementation in irritable bowel syndrome<\/p>\n<\/h3>\n
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FRIDAY, Aug. 6, 2021 (HealthDay News) — For patients with irritable bowel syndrome (IBS), vitamin D supplementation has no impact on improving symptom severity or quality of life, according to a study published online July 30 in the European Journal of Nutrition<\/em>.<\/p>\n Claire E. Williams, from the University of Sheffield in the United Kingdom, and colleagues examined whether vitamin D supplementation improves IBS symptoms in a randomized, double-blind, placebo-controlled trial. A total of 135 participants from the community received vitamin D or placebo for 12 weeks.<\/p>\n At baseline, 60 percent of the participants had deficient or insufficient vitamin D. The researchers observed an increase in vitamin D levels in the intervention arm versus the placebo arm (45.1 \u00c2\u00b1 32.88 nmol\/L versus 3.1 \u00c2\u00b1 26.15 nmol\/L; P < 0.001). However, no difference was seen in the change in IBS symptom severity over time between the intervention and placebo arms (\u00e2\u0088\u009262.5 \u00c2\u00b1 91.57 versus \u00e2\u0088\u009275.2 \u00c2\u00b1 84.35; P = 0.426). Similarly, no difference was seen in the change in quality of life between the intervention and placebo trial arms (\u00e2\u0088\u00927.7 \u00c2\u00b1 25.36 versus \u00e2\u0088\u009211.3 \u00c2\u00b1 25.02; P = 0.427).<\/p>\n “This study found no benefit of vitamin D supplementation on either symptoms of IBS or on quality of life measures using standardized assessments,” the authors write. “Notwithstanding any benefit of vitamin D on IBS symptomology, IBS patients should be screened for vitamin D status and supplemented appropriately for general health reasons.”<\/p>\n The study was partially funded by BetterYou Ltd., which supplied the vitamin D supplements.<\/p>\n Abstract\/Full Text (subscription or payment may be required)<\/a><\/p>\n <\/i><\/p>\n