<\/b><\/p>\n
<\/b><\/p>\n
THURSDAY, May 24, 2018 (HealthDay News) — A hyperactive and asymmetric velocity-storage mechanism may be responsible for intermittent attacks of vertigo in some patients with recurrent spontaneous vertigo (RSV) of unknown etiology, according to a study published online May 23 in Neurology<\/i>.<\/p>\n
Sun-Uk Lee, M.D., from the Seoul National University College of Medicine in South Korea, and colleagues compared headshaking nystagmus (HSN) in 35 patients with RSV-HSN to that recorded in randomly selected patients with compensated vestibular neuritis (VN), vestibular migraine (VM), and M\u00e9ni\u00e8re disease (MD).<\/p>\n
The researchers found that the estimated time constant of the primary phase of HSN was 12 seconds in patients with RSV-HSN, which was longer than those in patients with VN (5 seconds), VM (5 seconds), or MD (6 seconds). Seven of the 35 patients with RSV-HSN showed vigorous long-lasting HSN with a peak slow-phase velocity >50.0 degrees\/second. In five of these seven patients, HSN could have been induced even with head shaking for only 2 to 5 seconds. Over a median follow-up of 12 years from symptom onset, long-term prognosis was favorable, with a resolution or improvement of the symptoms in more than half of the patients, with none developing VM, MD, or cerebellar dysfunction.<\/p>\n
“The clinical features and characteristics of HSN in our patients indicate a hyperactive and asymmetric velocity-storage mechanism that gives rise to intermittent attacks of spontaneous vertigo probably when marginal compensation of underlying pathology is disrupted by endogenous or exogenous factors,” the authors write.<\/p>\n
Abstract\/Full Text (subscription or payment may be required)<\/a><\/p>\n Editorial (subscription or payment may be required)<\/a><\/p>\n <\/i><\/p>\n