After adjustment for multiple variables, stage 1 hypertension linked to acute coronary syndromes in women, but not men<\/p>\n<\/h3>\n
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MONDAY, May 17, 2021 (HealthDay News) — Stage 1 hypertension is associated with an increased risk for acute coronary syndromes (ACS) in women, according to a study published online May 16 in the European Journal of Preventive Cardiology<\/em>.<\/p>\n Ester Kringeland, M.D., from the University of Bergen in Norway, and colleagues examined associations between stage 1 hypertension and ACS in 12,329 participants in the Hordaland Health Study (mean baseline age, 41 years; 52 percent women). Participants were categorized by baseline blood pressure (BP) category: normotension (BP <130\/80 mm Hg), stage 1 hypertension (BP 130 to 139\/80 to 89 mm Hg), and stage 2 hypertension (BP \u00e2\u0089\u00a5140\/90 mm Hg).<\/p>\n The researchers found that during 16 years of follow-up, 1.4 and 5.7 percent of women and men, respectively, experienced incident ACS. Stage 1 hypertension was associated with a higher risk for ACS in women after adjustment for diabetes, smoking, body mass index, cholesterol, and physical activity (hazard ratio, 2.18; 95 percent confidence interval, 1.32 to 3.60), while in men, the association was not significant (hazard ratio, 1.30; 95 percent confidence interval, 0.98 to 1.71). Stage 1 diastolic hypertension was associated with ACS in women (hazard ratio, 2.54; 95 percent confidence interval, 1.56 to 4.15) but not in men (hazard ratio, 1.29; 95 percent confidence interval, 1.00 to 1.65), while stage 1 systolic hypertension was not associated with ACS in either sex after additional adjustment for systolic and diastolic BP.<\/p>\n “The results add to emerging evidence indicating that high blood pressure has particularly unfavorable effects on women’s hearts,” Kringeland said in a statement.<\/p>\n