Risk for uterine leiomyomata associated with ambient concentration of ozone, but not PM2.5 <\/sub> or NO2<\/sub><\/p>\n<\/h3>\n <\/b><\/p>\n <\/b><\/p>\n FRDAY, May 14, 2021 (HealthDay News) — Ozone (O3<\/sub>) concentrations are associated with an increased risk for uterine leiomyomata (UL) in Black women, according to a study published online May 13 in Human Reproduction<\/em>.<\/p>\n Amelia K. Wesselink, Ph.D., from the Boston University School of Public Health, and colleagues conducted a study involving 21,998 premenopausal Black women residing in 56 U.S. metropolitan areas from 1997 to 2011 to examine the association between ambient concentrations of particulate matter <2.5 microns (PM2.5<\/sub>), nitrogen dioxide (NO2<\/sub>), and O3<\/sub> with the risk for UL.<\/p>\n The researchers found that 28.4 percent of participants reported physician-diagnosed UL confirmed by ultrasound or surgery during 196,685 person-years of follow-up. There was no appreciable association seen for concentrations of PM2.5<\/sub> (hazard ratio for a one-interquartile range [IQR] increase, 1.01; 95 percent confidence interval, 0.93 to 1.10) or NO2<\/sub> (hazard ratio for a one-IQR increase, 1.05; 95 percent confidence interval, 0.95 to 1.16) with UL; however, O3<\/sub> concentrations were associated with an increased risk for UL (hazard ratio for a one-IQR increase, 1.19; 95 percent confidence interval, 1.07 to 1.32). Among women aged younger than 35 years and parous women, the association was stronger (hazard ratios, 1.26 [95 percent confidence interval, 0.98 to 1.62] and 1.28 [95 percent confidence interval, 1.11 to 1.48], respectively). <\/p>\n “There have now been three studies suggesting a link between air pollution and fibroids, but ours is the first to show this in Black women,” Wesselink said in a statement. “Because Black women are inequitably exposed to air pollution, these findings have important implications for racial disparity in fibroids.”<\/p>\n One author disclosed ties to the pharmaceutical and medical device industries.<\/p>\n Abstract\/Full Text (subscription or payment may be required)<\/a><\/p>\n <\/i><\/p>\n