Independent association found for lower BMD at lumbar spine, femur neck, total hip with higher risk for ASCVD events<\/p>\n<\/h3>\n
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FRIDAY, May 7, 2021 (HealthDay News) — Bone mineral density (BMD) has independent prognostic value for predicting atherosclerotic cardiovascular disease (ASCVD) in women, according to a study published online May 6 in Heart<\/em>.<\/p>\n Jiesuck Park, M.D., from the Seoul National University Bundang Hospital in South Korea, and colleagues examined the prognostic value of BMD for predicting ASCVD in women. A retrospective analysis was conducted among 12,681 women aged 50 to 80 years who underwent dual-energy X-ray absorptiometry. The hazard ratio for ASCVD events (ASCVD death, nonfatal myocardial infarction, and ischemic stroke) was assessed according to the BMD or a clinical diagnosis of osteopenia or osteoporosis.<\/p>\n The researchers found that during a median follow-up of 9.2 years, 468 women (3.7 percent) experienced ASCVD events. There was an independent association seen for lower BMD at the lumbar spine, femur neck, and total hip with a higher risk for ASCVD events (adjusted hazard ratio per 1-standard deviation decrease in BMD, 1.16). There was also an independent association observed for a clinical diagnosis of osteoporosis with a higher risk for ASCVD events (adjusted hazard ratio, 1.79). Significant incremental value was seen in discriminating ASCVD events with the addition of BMD or a clinical diagnosis of osteopenia or osteoporosis to clinical risk factors.<\/p>\n “The evaluation of BMD provides predictive value for ASCVD events in women,” the authors write. “Further studies are warranted to determine whether the evaluation of BMD translates into long-term clinical benefits in women.”<\/p>\n The study was partially funded by Hanmi Pharm. Co. Ltd.<\/p>\n Abstract\/Full Text<\/a><\/p>\n