More physical symptoms, immune irregularities seen at baseline in college students who develop postmononucleosis chronic fatigue syndrome<\/p>\n<\/h3>\n
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THURSDAY, Feb. 4, 2021 (HealthDay News) — Many college students fully recover from infectious mononucleosis (IM) within six weeks, but nearly one-quarter go on to develop chronic fatigue syndrome (CFS), according to a study recently published in Clinical Infectious Diseases<\/em>.<\/p>\n Leonard A. Jason, Ph.D., from DePaul University in Chicago, and colleagues examined predictors of myalgic encephalomyelitis\/CFS (ME\/CFS) among 4,501 college students.<\/p>\n The researchers found that 5.3 percent developed IM, and six months later, 55 of 238 (23 percent) met criteria for ME\/CFS and 157 (66 percent) were asymptomatic. Using 67 of the 157 asymptomatic students as controls, the researchers observed no differences between students with severe ME\/CFS and those who were asymptomatic in terms of stress, coping, anxiety, or depression. However, there were differences noted in several behavioral measures, and those with severe ME\/CFS had significantly lower levels of interleukin (IL)-6 and IL-13. At diagnosis, the two ME\/CFS groups tended to have more autonomic complaints and behavioral symptoms, while the severe ME\/CFS group had higher levels of IL-12 and lower levels of IL-13 than the recovered group.<\/p>\n “At baseline, those who developed ME\/CFS had more physical symptoms and immune irregularities, but not more psychological symptoms, than those who recovered,” the authors write.<\/p>\n Abstract\/Full Text (subscription or payment may be required)<\/a><\/p>\n <\/i><\/p>\n