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Here is what the editors at Physician’s Briefing chose as the most important COVID-19 developments for you and your practice for the week of Jan. 25 to 29, 2021. This roundup includes the latest research news from journal studies and other trusted sources that is most likely to affect clinical practice.<\/p>\n
New COVID-19 Variants May Weaken Efficacy of Vaccines<\/strong><\/p>\n FRIDAY, Jan. 29, 2021 (HealthDay News) — The new coronavirus is mutating in an attempt to elude vaccines and treatments, putting a greater onus on Americans to get vaccinated and use social distancing measures to avoid infection, U.S. health officials said Friday.<\/p>\n Read Full Text<\/a><\/p>\n SARS-CoV-2 Seroconversion Tied to Out-of-Hospital Sudden Deaths<\/strong><\/p>\n FRIDAY, Jan. 29, 2021 (HealthDay News) — There was an association between geographic distribution of out-of-hospital sudden death and epidemiologic burden of severe acute respiratory syndrome coronavirus 2 in New York City during the first epidemic outbreak, according to a study published in the February issue of Heart Rhythm<\/em>.<\/p>\n Read Full Text<\/a><\/p>\n EU Regulator Approves Oxford-AstraZeneca COVID-19 Vaccine<\/strong><\/p>\n FRIDAY, Jan. 29, 2021 (HealthDay News) — European Union regulators have authorized the AstraZeneca COVID-19 vaccine for use in adults, CBS News<\/em> reported Friday.<\/p>\n Read Full Text<\/a><\/p>\n Nearly Half of U.S. Adults Want the COVID-19 Vaccine as Soon as Possible<\/strong><\/p>\n FRIDAY, Jan. 29, 2021 (HealthDay News) — U.S. adults are increasingly eager to get the COVID-19 vaccine, according to survey results released by the Kaiser Family Foundation COVID-19 Vaccine Monitor.<\/p>\n Read Full Text<\/a><\/p>\n J&J COVID-19 Vaccine 66 Percent Effective in Interim Analysis<\/strong><\/p>\n FRIDAY, Jan. 29, 2021 (HealthDay News) — Interim phase 3 data show that the COVID-19 vaccine developed by Janssen Pharmaceuticals of Johnson & Johnson is 66 percent effective in preventing moderate-to-severe COVID-19 in adults, the National Institutes of Health announced today.<\/p>\n Read Full Text<\/a><\/p>\n COVID-19 Admissions, Fatalities Up for Pregnant Women<\/strong><\/p>\n FRIDAY, Jan. 29, 2021 (HealthDay News) — Compared with similarly aged adults in Washington state, pregnant women have significantly higher COVID-19 hospitalization and case fatality rates, according to a study published online Jan. 26 in the American Journal of Obstetrics & Gynecology<\/em>.<\/p>\n Read Full Text<\/a><\/p>\n Schizophrenia Linked to Mortality in Adults With COVID-19<\/strong><\/p>\n FRIDAY, Jan. 29, 2021 (HealthDay News) — A premorbid diagnosis of schizophrenia spectrum disorder is associated with mortality among adults with COVID-19, according to a study published online Jan. 27 in JAMA Psychiatry<\/em>.<\/p>\n Read Full Text<\/a><\/p>\n Guidance Issued for COVID-19 Vaccination of Cancer Patients<\/strong><\/p>\n THURSDAY, Jan. 28, 2021 (HealthDay News) — In a new guidance statement from the National Comprehensive Cancer Network, recommendations are presented for COVID-19 vaccination of cancer patients.<\/p>\n Read Full Text<\/a><\/p>\n Early Anticoagulation May Not Up Survival in Severe COVID-19<\/strong><\/p>\n THURSDAY, Jan. 28, 2021 (HealthDay News) — Early therapeutic anticoagulation does not appear to affect survival among critically ill adults with COVID-19, according to a study published online Jan. 26 in the Annals of Internal Medicine<\/em>.<\/p>\n Read Full Text<\/a><\/p>\n Retired Doctors, Nurses Will Be Approved to Give COVID-19 Vaccine, White House Says<\/strong><\/p>\n WEDNESDAY, Jan. 27, 2021 (HealthDay News) — Retired doctors and nurses are being called to the front lines of the U.S. COVID-19 vaccination effort, the White House COVID-19 Response team announced Wednesday.<\/p>\n Read Full Text<\/a><\/p>\n Respiratory, Physical, Psych Sequelae ID’d After COVID-19 Discharge<\/strong><\/p>\n WEDNESDAY, Jan. 27, 2021 (HealthDay News) — For patients hospitalized with COVID-19, respiratory, physical, and psychological sequelae are common at four months after discharge, according to a study published online Jan. 27 in JAMA Network Open<\/em>.<\/p>\n Read Full Text<\/a><\/p>\n U.S. Government to Increase Vaccine Deliveries to States<\/strong><\/p>\n WEDNESDAY, Jan. 27, 2021 (HealthDay News) — In response to COVID-19 vaccine shortages, the U.S. government will increase vaccine deliveries to states by 16 percent during the next three weeks and plans to have enough to vaccinate 300 million people by the end of summer or early fall, President Joe Biden said Tuesday.<\/p>\n Read Full Text<\/a><\/p>\n Certain Factors Increase Pandemic’s Psychological Impact on College Students<\/strong><\/p>\n WEDNESDAY, Jan. 27, 2021 (HealthDay News) — Certain risk factors are associated with college students self-reporting a psychological impact of the COVID-19 pandemic, according to a study published online Jan. 7 in PLOS ONE<\/em>.<\/p>\n Read Full Text<\/a><\/p>\n COVID-19 Antibody Treatments Exceed Expectations in Early Trials<\/strong><\/p>\n WEDNESDAY, Jan. 27, 2021 (HealthDay News) — Promising new data on two antibody cocktails suggest these therapies can keep COVID-19 patients out of the hospital and even prevent illness altogether in some people.<\/p>\n Read Full Text<\/a><\/p>\n Metformin Use for T2DM May Reduce COVID-19 Mortality<\/strong><\/p>\n WEDNESDAY, Jan. 27, 2021 (HealthDay News) — Diabetes is associated with increased odds of contracting COVID-19 and with increased COVID-19 mortality, while metformin treatment before diagnosis of COVID-19 is associated with reduced odds of related mortality, according to a study published online Jan. 13 in Frontiers in Endocrinology<\/em>.<\/p>\n Read Full Text<\/a><\/p>\n Large Number of SARS-CoV-2-Infected Are Asymptomatic<\/strong><\/p>\n TUESDAY, Jan. 26, 2021 (HealthDay News) — Nearly three-quarters of individuals with severe acute respiratory syndrome coronavirus 2 infection remain asymptomatic, according to a systematic review published online Jan. 22 in the Annals of Internal Medicine<\/em>.<\/p>\n Read Full Text<\/a><\/p>\n Anxiety, Depression Remain High Following Initial Lockdown<\/strong><\/p>\n TUESDAY, Jan. 26, 2021 (HealthDay News) — Depression and anxiety rates remain elevated following the initial COVID-19 lockdown, according to a study published online Jan. 11 in the Journal of Public Health<\/em>.<\/p>\n Read Full Text<\/a><\/p>\n Brazilian Coronavirus Variant Found in Minnesota<\/strong><\/p>\n TUESDAY, Jan. 26, 2021 (HealthDay News) — The first known U.S. case of a more infectious Brazilian variant of the coronavirus has been confirmed in a person in Minnesota who recently traveled to Brazil, state health officials said Monday.<\/p>\n Read Full Text<\/a><\/p>\n COVID-19 Also Hazardous for Middle-Aged Adults<\/strong><\/p>\n TUESDAY, Jan. 26, 2021 (HealthDay News) — COVID-19 is dangerous for middle-aged adults, with an estimated age-specific infection fatality rate of 0.4 and 1.4 percent at ages 55 and 65 years, respectively, according to a review published online Dec. 8 in the European Journal of Epidemiology<\/em>.<\/p>\n Read Full Text<\/a><\/p>\n Smoking History Tied to Worse COVID-19 Outcomes<\/strong><\/p>\n TUESDAY, Jan. 26, 2021 (HealthDay News) — Cumulative cigarette smoke exposure is an independent risk factor for hospital admission and death from COVID-19, according to a research letter published online Jan. 25 in JAMA Internal Medicine<\/em>.<\/p>\n Read Full Text<\/a><\/p>\n COVID-19 Outcomes No Worse for Patients on Immunosuppressive Meds<\/strong><\/p>\n TUESDAY, Jan. 26, 2021 (HealthDay News) — People taking immunosuppressive drugs prior to a COVID-19 hospitalization do not have worse outcomes, according to a study published online Jan. 7 in Clinical Infectious Diseases<\/em>.<\/p>\n Read Full Text<\/a><\/p>\n No Evidence Found to Support Discontinuing ACEIs, ARBs in COVID-19<\/strong><\/p>\n TUESDAY, Jan. 26, 2021 (HealthDay News) — For patients taking angiotensin-converting enzyme inhibitors or angiotensin II receptor blockers and hospitalized with mild-to-moderate COVID-19, there is no significant difference in the mean number of days alive and out of the hospital with discontinuation or continuation of these medications, according to a study published in the Jan. 19 issue of the Journal of the American Medical Association<\/em>.<\/p>\n Read Full Text<\/a><\/p>\n U.S. to Get Fewer Vials of Pfizer COVID-19 Vaccine<\/strong><\/p>\n MONDAY, Jan. 25, 2021 (HealthDay News) — Pfizer will provide fewer vials of its COVID-19 vaccine to the United States in the coming months after it was discovered that it had previously shipped extra doses.<\/p>\n Read Full Text<\/a><\/p>\n Moderna COVID-19 Vaccine Effective Against British, South African Variants<\/strong><\/p>\n MONDAY, Jan. 25, 2021 (HealthDay News) — Moderna says its COVID-19 vaccine remains effective against two worrisome new coronavirus variants from Britain and South Africa, but it is somewhat less effective against the South African variant.<\/p>\n Read Full Text<\/a><\/p>\n 2.5 Anaphylaxis Cases Reported Per Million COVID-19 Moderna Vaccine Shots<\/strong><\/p>\n MONDAY, Jan. 25, 2021 (HealthDay News) — The rate of anaphylaxis is 2.5 cases per million Moderna COVID-19 vaccine doses administered as of Jan. 10, 2021, according to research published in the Jan. 22 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report<\/em>.<\/p>\n Read Full Text<\/a><\/p>\n Full-Dose Heparin May Aid Moderately Ill COVID-19 Patients<\/strong><\/p>\n MONDAY, Jan. 25, 2021 (HealthDay News) — Evidence suggests that full-dose anticoagulation treatment reduces the need for vital organ support such as ventilation and may reduce mortality in moderately ill patients hospitalized with COVID-19, according to interim results of research funded by the National Health, Lung, and Blood Institute.<\/p>\n Read Full Text<\/a><\/p>\n Vitamin D Deficiency Associated With Increased COVID-19 Risk<\/strong><\/p>\n MONDAY, Jan. 25, 2021 (HealthDay News) — Patients with vitamin D deficiency are significantly more likely to be positive for COVID-19, according to a study published in the April issue of Nutrition<\/em>.<\/p>\n Read Full Text<\/a><\/p>\n Children Less Susceptible to SARS-CoV-2 but More Infectious<\/strong><\/p>\n MONDAY, Jan. 25, 2021 (HealthDay News) — Children and adolescents are less susceptible to severe acute respiratory syndrome coronavirus 2 infection, but are more infectious than older adults within households, according to a study published online Jan. 18 in The Lancet Infectious Diseases<\/em>.<\/p>\n