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MONDAY, Oct. 19, 2020 (HealthDay News) — Most patients with congenital heart disease (CHD) are not at risk for severe COVID-19 infection, according to a study published online Oct. 14 in the Journal of the American Heart Association<\/i>.<\/p>\n
Matthew J. Lewis, M.D., from the Columbia University Irving Medical Center in New York City, and colleagues assessed the impact and predictors of COVID-19 infection and severity among 53 patients with CHD diagnosed with COVID-19 between March 1 and July 1, 2020.<\/p>\n
The researchers found that 10 CHD patients were younger than 18 years old (median age, 34 years). More than half (58 percent) had complex congenital anatomy, including 10 with a Fontan repair. Additionally, eight patients had a genetic syndrome, six had pulmonary hypertension, and nine were obese. Eighteen adults were physiologic class C or D. Among all 53 patients, nine had a moderate or severe infection, including three who died. The presence of a genetic syndrome (odds ratio, 35.82) and physiological Stage C or D in adults (odds ratio, 19.38) were significantly associated with moderate or severe infection.<\/p>\n
“While our sample size is small, these results imply that specific congenital heart lesions may not be sufficient cause alone for severe COVID-19 infection,” the authors write.<\/p>\n
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