<\/b><\/p>\n
<\/b><\/p>\n
WEDNESDAY, Aug. 26, 2020 (HealthDay News) — An intensive lifestyle intervention (ILI) may reduce the incidence of obesity-related mortality among individuals with overweight or obesity and type 2 diabetes, according to a study published online Aug. 24 in Obesity<\/i>.<\/p>\n
Hsin-Chieh Yeh, Ph.D., from Johns Hopkins University in Baltimore, and colleagues examined data from the Look AHEAD trial, involving adults with overweight or obesity and type 2 diabetes, to examine cancer incidence, obesity-related cancer incidence, and cancer mortality for participants randomly assigned to ILI designed for weight loss compared with a diabetes support and education (DSE) comparison group. A total of 4,859 participants without a cancer diagnosis at baseline were included in the analysis.<\/p>\n
The researchers found that 684 participants (332 in the ILI group and 352 in the DSE group) were diagnosed with cancer after a median follow-up of 11 years. In the ILI and DSE groups, the incidence rates of obesity-related cancers were 6.1 and 7.3 per 1,000 person-years, respectively, with a hazard ratio of 0.84 (95 percent confidence interval, 0.68 to 1.04). No significant between-group differences were seen in total cancer incidence (hazard ratio, 0.93; 95 percent confidence interval, 0.80 to 1.08), incidence of non-obesity-related cancers (hazard ratio, 1.02; 95 percent confidence interval, 0.83 to 1.27), or total cancer mortality (hazard ratio, 0.92; 95 percent confidence interval, 0.68 to 1.25).<\/p>\n
“Although the result was not statistically significant, this finding provided evidence that patients with obesity can reduce their cancer risk through weight loss,” the authors write.<\/p>\n
One author disclosed financial ties to WW, formerly Weight Watchers.<\/p>\n
Abstract\/Full Text (subscription or payment may be required)<\/a><\/p>\n Editorial (subscription or payment may be required)<\/a><\/p>\n <\/i><\/p>\n