{"id":34579,"date":"2020-05-13T00:00:00","date_gmt":"2020-05-13T00:00:00","guid":{"rendered":"http:\/\/medgoo.com\/index.php\/2020\/05\/13\/pm2-5-linked-to-later-mortality-in-certain-pediatric-aya-cancers\/"},"modified":"2020-05-14T16:10:15","modified_gmt":"2020-05-14T16:10:15","slug":"pm2-5-linked-to-later-mortality-in-certain-pediatric-aya-cancers","status":"publish","type":"post","link":"https:\/\/medgoo.com\/index.php\/2020\/05\/13\/pm2-5-linked-to-later-mortality-in-certain-pediatric-aya-cancers\/","title":{"rendered":"PM<sub>2.5<\/sub> Linked to Later Mortality in Certain Pediatric, AYA Cancers"},"content":{"rendered":"<h3>Mortality risk increased at 5 years, 10 years among those with pediatric lymphomas, CNS tumors<\/h3>\n<p><b><\/b><\/p>\n<p><b><\/b><\/p>\n<p>WEDNESDAY, May 13, 2020 (HealthDay News) &#8212; For pediatric and adolescent and young adult (AYA) patients with specific cancers, continued exposure to fine particulate matter (PM<sub>2.5<\/sub>) is associated with later mortality, according to a study published online May 13 in <i>Cancer, Epidemiology, Biomarkers &#038; Prevention<\/i>.<\/p>\n<p>Judy Y. Ou, Ph.D., from the University of Utah in Salt Lake City, and colleagues followed 2,444 pediatric and 13,459 AYA patients (diagnosed during 1986 to 2015 at ages 0 to 14 and 15 to 39 years, respectively) from diagnosis to five and 10 years postdiagnosis, death, or emigration. During follow-up, the average monthly PM<sub>2.5<\/sub> was measured by ZIP code.<\/p>\n<p>The researchers observed an association between increases in PM<sub>2.5<\/sub> per 5 \u00b5g\/m\u00b3 and cancer mortality in pediatric lymphomas and central nervous system (CNS) tumors at both time points and for all-cause mortality in lymphoid leukemias (hazard ratio<sub>5-year<\/sub> = 1.32). Among AYAs, at both time points, PM<sub>2.5<\/sub> per 5 \u00b5g\/m\u00b3 was associated with cancer mortality in CNS tumors and carcinomas and with all-cause mortality for all AYA cancer types (hazard ratio<sub>5-year<\/sub> = 1.06). At both time points, PM<sub>2.5<\/sub> \u226512 \u00b5g\/m\u00b3 was associated with cancer mortality among breast and colorectal cancers. There was significant effect modification by stage, with the highest risk for local tumors.<\/p>\n<p>&#8220;While improvements in detection and treatment are of great importance to reducing cancer mortality, understanding how continued exposure to pollutants with known carcinogenic effects such as PM<sub>2.5<\/sub> is also important but largely unknown,&#8221; the authors write.<\/p>\n<p><a href=\"https:\/\/cebp.aacrjournals.org\/content\/early\/2020\/05\/08\/1055-9965.EPI-19-1363\" target=\"_new\" rel=\"noopener noreferrer\">Abstract\/Full Text (subscription or payment may be required)<\/a><\/p>\n<p><i><\/i><\/p>\n<p><i>Copyright \u00a9 2020 <a href=\"https:\/\/www.healthday.com\/\" target=\"_new\" rel=\"noopener noreferrer\">HealthDay<\/a>. All rights reserved.<\/i><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Mortality risk increased at 5 years, 10 years among those with pediatric lymphomas, CNS tumors<\/p>\n","protected":false},"author":6,"featured_media":34612,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[6],"tags":[11],"class_list":["post-34579","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news","tag-news"],"_links":{"self":[{"href":"https:\/\/medgoo.com\/index.php\/wp-json\/wp\/v2\/posts\/34579","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medgoo.com\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/medgoo.com\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/medgoo.com\/index.php\/wp-json\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"https:\/\/medgoo.com\/index.php\/wp-json\/wp\/v2\/comments?post=34579"}],"version-history":[{"count":0,"href":"https:\/\/medgoo.com\/index.php\/wp-json\/wp\/v2\/posts\/34579\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medgoo.com\/index.php\/wp-json\/wp\/v2\/media\/34612"}],"wp:attachment":[{"href":"https:\/\/medgoo.com\/index.php\/wp-json\/wp\/v2\/media?parent=34579"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/medgoo.com\/index.php\/wp-json\/wp\/v2\/categories?post=34579"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/medgoo.com\/index.php\/wp-json\/wp\/v2\/tags?post=34579"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}