<\/b><\/p>\n
<\/b><\/p>\n
WEDNESDAY, April 1, 2020 (HealthDay News) — For patients with type 2 diabetes (T2D), glycemic control is similar with use of regular human insulin (RHI) and rapid-acting insulin (RAI) when delivered with a wearable insulin delivery device, V-Go, according to a study presented at the virtual meeting of The Endocrine Society, held from March 28 to 31.<\/p>\n
Pablo Mora, M.D., from the Dallas Diabetes Research Center, and colleagues conducted a noninferiority study in a population with T2D to compare the efficacy and safety of RAI versus RHI when delivered by V-Go. Data were assessed from 113 patients, including 59 with RHI and 54 with RAI.<\/p>\n
The researchers found that the mean change in hemoglobin A1c was \u22120.60 percent from a baseline of 8.41 percent with RHI versus \u22120.38 percent from a baseline of 8.33 percent with RAI (estimated treatment difference [ETD], \u22120.22 percent; 95 percent confidence interval, \u22120.67 to 0.22 percent; noninferiority margin < 0.4 percent and P = 0.007). The mean change in total daily dose was 0.8 U\/day from a baseline of 61.0 U\/day with RHI versus 1.8 U\/day from a baseline of 61.3 U\/day with RAI (ETD, \u22121.04 U\/day; 95 percent confidence interval, \u22123.18 to 1.11 U\/day; P = 0.92). From prerandomization to postrandomization, the absolute change in percent of patients reporting hypoglycemia was +5.08 and +5.56 percent with RHI and RAI, respectively (ETD, \u22120.48 percent; 95 percent confidence interval, \u221210.6 to 9.1 percent; P = 0.91).<\/p>\n
“Use of RHI with V-Go expands the affordability of insulin therapy,” a coauthor said in a statement.<\/p>\n
One author disclosed financial ties to Valeritas, the manufacturer the V-Go device.<\/p>\n
Press Release<\/a><\/p>\n