<\/b><\/p>\n
<\/b><\/p>\n
THURSDAY, Feb. 20, 2020 (HealthDay News) — Early-adolescent and young adult cancer survivors have increased mortality and morbidity risks compared with siblings or the general population, according to a study published online Feb. 14 in The Lancet Oncology<\/i>.<\/p>\n
Eugene Suh, M.D., from Loyola University Chicago Health Sciences, and colleagues used data from the Childhood Cancer Survivor Study to describe chronic health conditions and all-cause and cause-specific mortality among survivors of early-adolescent and young adult cancer (aged 15 to 20 years at diagnosis; 5,804 survivors) and survivors diagnosed at an age younger than 15 years (5,804 survivors) compared with a cohort of siblings and the general population.<\/p>\n
The researchers found that the standardized mortality ratio (SMR) for all-cause mortality was 5.9 and 6.2 among early-adolescent and young adult survivors and childhood cancer survivors, respectively, compared with the general population. Compared with childhood cancer survivors, early-adolescent and young adult cancer survivors had lower SMRs for death from health-related causes (SMR, 4.8 versus 6.8), which was mainly evident more than 20 years after cancer diagnosis. The risk for developing severe and disabling, life-threatening, or fatal health conditions was increased for early-adolescent and young adult cancer survivors and childhood cancer survivors versus siblings of the same age (hazard ratios, 4.2 and 5.6, respectively).<\/p>\n
“Our data underscore that focused efforts are needed to ensure early-adolescent and young adult cancer survivors are receiving recommended risk-based care, with a focus on high-risk cancer screening, to reduce morbidity and premature mortality,” the authors write.<\/p>\n
One author disclosed financial ties to Novo Nordisk.<\/p>\n
Abstract\/Full Text (subscription or payment may be required)<\/a><\/p>\n Editorial (subscription or payment may be required)<\/a><\/p>\n <\/i><\/p>\n