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THURSDAY, Jan. 16, 2020 (HealthDay News) — A behavioral intervention that increases vegetable consumption does not reduce the risk for progression of early-stage prostate cancer, according to a study published in the Jan. 14 issue of the Journal of the American Medical Association<\/i>.<\/p>\n
J. Kellogg Parsons, M.D., from the UC San Diego Moores Comprehensive Cancer Center in La Jolla, California, and colleagues randomly assigned 478 men aged 50 to 80 years with biopsy-proven prostate adenocarcinoma, stage cT2a or less, to either a counseling behavioral intervention by telephone promoting consumption of seven or more daily vegetable servings or a control group that received written information about diet and prostate cancer (237 and 241 men, respectively). The primary analysis included 443 men.<\/p>\n
The researchers identified 245 progression events (124 and 121 in the intervention and control groups, respectively). Time to progression did not differ significantly between the groups (unadjusted hazard ratio, 0.96 [95 percent confidence interval, 0.75 to 1.24]; adjusted hazard ratio, 0.97 [95 percent confidence interval, 0.76 to 1.25]). For the intervention and control groups, the 24-month Kaplan-Meier progression-free percentages were 43.5 and 41.4 percent, respectively (difference, 2.1 percent; 95 percent confidence interval, \u22128.1 to 12.2 percent).<\/p>\n
“We now have good evidence that a diet rich in fruits and vegetables and light on red meat is not likely to impact need for treatment,” a coauthor said in a statement. “But this study does not provide justification for eating anything you want, either.”<\/p>\n
Several authors disclosed financial ties to the pharmaceutical industry.<\/p>\n
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