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FRIDAY, March 30, 2018 (HealthDay News) — Children with high irritability and depressive\/anxious mood have increased suicidality risk during adolescence, according to a study published online March 28 in JAMA Psychiatry<\/i>.<\/p>\n
Massimiliano Orri, Ph.D., from the Institut National de la Sant\u00e9 et de la Recherche Medicale in Bordeaux, France, and colleagues examined the correlation of childhood irritability and depressive\/anxious mood profiles with adolescent suicidality in a population-based cohort study. A total of 1,430 participants in the Qu\u00e9bec Longitudinal Study of Child Development were assessed yearly or bi-yearly from 5 months to 17 years of age.<\/p>\n
The researchers found that, compared to the group with the lowest symptom levels, children with high irritability and high depressive\/anxious mood reported higher rates of suicidality (16.4 versus 11.0 percent). There was a correlation for the high irritability and depressive\/anxious mood profile with suicidality (odds ratio, 2.22); the moderate irritability and low depressive\/anxious mood profile was also linked to suicidality, but to a lesser extent (odds ratio, 1.51). Compared with the depressive\/anxious mood only profile, the high irritability and depressive\/anxious mood profile correlated with a higher suicidal risk (odds ratio, 2.28). Higher risk of suicidality was seen for girls with the high irritability and high depressive\/anxious mood profile (odds ratio, 3.07).<\/p>\n
“Early manifestation of chronic irritability during childhood, especially when combined with depressive\/anxious mood, may be associated with an elevated risk for adolescent suicidality,” the authors write.<\/p>\n
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