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FRIDAY, Nov. 8, 2019 (HealthDay News) — Supplementation with vitamin D3<\/sub> or omega-3 fatty acids does not result in a significant difference in change in estimated glomerular filtration rate (eGFR) at five years versus placebo among adults with type 2 diabetes, according to a study published online Nov. 8 in the Journal of the American Medical Association<\/i>. The research was published to coincide with Kidney Week, the annual meeting of the American Society of Nephrology, held from Nov. 5 to 10 in Washington, D.C.<\/p>\n Ian H. de Boer, M.D., from the University of Washington in Seattle, and colleagues conducted a randomized trial among 1,312 adults with type 2 diabetes. Participants were randomly assigned to receive vitamin D3<\/sub> and omega-3 fatty acids, vitamin D3<\/sub> and placebo, placebo and omega-3 fatty acids, or two placebos (370, 333, 289, and 320 participants, respectively) for five years; 71 percent completed the study.<\/p>\n The researchers found that from baseline to year 5, the mean change in eGFR was \u221212.3 versus \u221213.1 mL\/min\/1.73 m\u00b2 with vitamin D3<\/sub> versus placebo (difference, 0.9; 95 percent confidence interval, \u22120.7 to 2.5). The mean change in eGFR was \u221212.2 versus \u221213.1 mL\/min\/1.73 m\u00b2 with omega-3 fatty acids versus placebo (difference, 0.9; 95 percent confidence interval, \u22120.7 to 2.6). No significant interaction was seen between the two interventions.<\/p>\n “These results suggest that neither vitamin D nor omega-3 fatty acids have appreciable kidney benefits among the broad population of patients with diagnosed type 2 diabetes,” the authors write.<\/p>\n Several authors disclosed financial ties to the pharmaceutical industry; one author disclosed holding a patent pending on a measurement of bioavailable vitamin D.<\/p>\n Abstract\/Full Text (subscription or payment may be required)<\/a><\/p>\n Editorial (subscription or payment may be required)<\/a><\/p>\n