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MONDAY, Oct. 21, 2019 (HealthDay News) — Intrauterine growth restriction protects against allergic diseases, according to a review published online Oct. 12 in the Journal of Allergy and Clinical Immunology<\/i>.<\/p>\n
Amy L. Wooldridge, Ph.D., from University of Adelaide in Australia, and colleagues conducted a systematic literature review to identify studies evaluating the association between prenatal growth and susceptibility to allergy.<\/p>\n
The researchers identified 42 eligible studies, including prospective and retrospective cohort, cross-sectional, and case-control studies. Allergic asthma was investigated in only two studies. A 1-kg increase in birth weight was associated with a greater risk for food allergy in children (odds ratio, 1.44), a greater risk for ever allergic dermatitis in children (odds ratio, 1.17), and a greater risk for ever or current allergic dermatitis in infants up to 2 years of age (odds ratio, 1.34). There was no association noted between risk for allergic rhinitis and birth weight.<\/p>\n
“It is increasingly clear that genetics alone do not explain risks of developing allergies, and that environmental exposures before and around birth can program individuals to increased or decreased risk of allergies,” a coauthor said in a statement.<\/p>\n
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