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TUESDAY, Sept. 17, 2019 (HealthDay News) — Prenatal and postnatal exposure to chemicals, environment, and meteorological factors may impact blood pressure (BP) in children, according to a study published in the Sept. 10 issue of the Journal of the American College of Cardiology<\/i>.<\/p>\n
Charline Warembourg, Ph.D., from ISGlobal in Barcelona, Spain, and colleagues examined the correlation between prenatal and postnatal exposures and BP in 1,277 children aged 6 to 11 years. Exposures included air pollution, built environment, meteorology, natural spaces, traffic, noise, chemicals, and lifestyles.<\/p>\n
The researchers identified decreases in systolic BP with facility density, maternal concentrations of polychlorinated biphenyl 118 and child concentrations of dichlorodiphenyldichloroethylene (DDE), hexachlorobenzene, and mono-benzyl phthalate (\u03b2 change for an interquartile-range increase in exposure: \u22121.7 [95 percent confidence interval, \u22122.5 to \u22120.8], \u22121.4 [\u22122.6 to \u22120.2], \u22121.6 [\u22122.4 to \u22120.7], \u22121.5 [\u22122.4 to \u22120.6], and \u22120.7 [\u22121.3 to \u22120.1] mm Hg, respectively). Outdoor temperature during pregnancy, high fish intake during pregnancy, maternal cotinine concentrations, and child perfluorooctanoate concentrations were associated with increases in systolic BP (1.6 [0.2 to 2.9], 2.0 [0.4 to 3.5], 1.2 [\u22120.3 to 2.8], and 0.9 [0.1 to 1.6] mm Hg, respectively). There was a decrease in diastolic BP with outdoor temperature at examination and child DDE concentrations (\u22121.4 [\u22122.3 to \u22120.5] and \u22121.1 [\u22121.9 to \u22120.3] mm Hg, respectively); maternal bisphenol-A concentrations, high fish intake during pregnancy, and child copper concentrations were associated with increases in diastolic BP (0.7 [0.1 to 1.4], 1.2 [\u22120.2 to 2.7], and 0.9 [0.3 to 1.6] mm Hg, respectively).<\/p>\n
“The clinical impact of the associations reported remains to be evaluated, but the unique strength of the longitudinal cohorts should be fostered to implement follow-ups that allow the investigation of long-term health implications,” the authors write.<\/p>\n
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