{"id":23177,"date":"2019-07-25T00:00:00","date_gmt":"2019-07-25T00:00:00","guid":{"rendered":"http:\/\/medgoo.com\/index.php\/2019\/07\/25\/first-u-s-trial-using-crispr-within-the-body-set-to-begin\/"},"modified":"2019-07-26T16:07:23","modified_gmt":"2019-07-26T16:07:23","slug":"first-u-s-trial-using-crispr-within-the-body-set-to-begin","status":"publish","type":"post","link":"https:\/\/medgoo.com\/index.php\/2019\/07\/25\/first-u-s-trial-using-crispr-within-the-body-set-to-begin\/","title":{"rendered":"First U.S. Trial Using CRISPR Within the Body Set to Begin"},"content":{"rendered":"<h3>Researchers will attempt to give patients with Leber congenital amaurosis a healthy version of the gene they lack<\/h3>\n<p><b><\/b><\/p>\n<p><b><\/b><\/p>\n<p>THURSDAY, July 25, 2019 (HealthDay News) &#8212; In a U.S. first, a clinical trial to begin this fall will use the inside-the-body gene-editing technique CRISPR to try to cure illness. Doctors hope to use the cutting-edge technique to cure the inherited form of blindness known as Leber congenital amaurosis.<\/p>\n<p>Using a tool that cuts or &#8220;edits&#8221; DNA in a specific spot, researchers will attempt to give pediatric and adult patients a healthy version of the gene they lack. The trial will include 18 people across the United States and will be conducted by two companies, Editas Medicine and Allergan, the <i>Associated Press<\/i> reported.<\/p>\n<p>Leber congenital amaurosis is the most common cause of inherited childhood blindness, occurring in about two to three of every 100,000 births.<\/p>\n<p>The only other trial to use gene editing inside the body was to treat metabolic diseases. That was done by a company called Sangamo Therapeutics, the <i>AP<\/i> reported.<\/p>\n<p><a href=\"https:\/\/www.apnews.com\/132d29e760834699b12c0c5b0a77e4c0\" target=\"_new\" rel=\"noopener noreferrer\"><i>AP News<\/i> Article<\/a><\/p>\n<p><i><\/i><\/p>\n<p><i>Copyright \u00a9 2019 <a href=\"https:\/\/www.healthday.com\/\" target=\"_new\" rel=\"noopener noreferrer\">HealthDay<\/a>. All rights reserved.<\/i><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Researchers will attempt to give patients with Leber congenital amaurosis a healthy version of the gene they lack<\/p>\n","protected":false},"author":6,"featured_media":23197,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[6],"tags":[11],"class_list":["post-23177","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news","tag-news"],"_links":{"self":[{"href":"https:\/\/medgoo.com\/index.php\/wp-json\/wp\/v2\/posts\/23177","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medgoo.com\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/medgoo.com\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/medgoo.com\/index.php\/wp-json\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"https:\/\/medgoo.com\/index.php\/wp-json\/wp\/v2\/comments?post=23177"}],"version-history":[{"count":0,"href":"https:\/\/medgoo.com\/index.php\/wp-json\/wp\/v2\/posts\/23177\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medgoo.com\/index.php\/wp-json\/wp\/v2\/media\/23197"}],"wp:attachment":[{"href":"https:\/\/medgoo.com\/index.php\/wp-json\/wp\/v2\/media?parent=23177"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/medgoo.com\/index.php\/wp-json\/wp\/v2\/categories?post=23177"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/medgoo.com\/index.php\/wp-json\/wp\/v2\/tags?post=23177"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}