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TUESDAY, July 16, 2019 (HealthDay News) — Living donor liver transplant (LDLT) offers superior outcomes and less resource utilization over deceased donor liver transplant (DDLT), according to research published online July 10 in the Annals of Surgery<\/i>.<\/p>\n
Abhinav Humar, M.D., from the University of Pittsburgh, and colleagues conducted a retrospective review of 245 adult LDLT and 592 adult DDLT performed at a single center during 10 years.<\/p>\n
The researchers found that LDLT recipients had superior patient survival outcomes at three years (86 versus 80 percent). LDLT recipients also had a significantly shorter length of hospital stay (11 versus 13 days) as well as a lower likelihood of intraoperative blood transfusion (52 versus 78 percent) and need for posttransplant dialysis (1.6 versus 7.4 percent). Rates of early reoperation and biliary\/vascular complications were similar. LDLT had 29.5 percent lower hospital costs related to the transplant. For LDLT, researchers found no early or late deaths, a 3.1 percent three-month reoperation rate, and an overall complication rate of 19.5 percent. Use of LDLT expanded in the center, comprising 53.6 percent of transplants (versus a national average of 4.8 percent), with the transplant rate increasing from 44.8 per 100 person-years in 2015 to 87.5 in 2018.<\/p>\n
“Living donor liver transplants, in tandem with deceased donor liver transplants, [represent] an opportunity to significantly decrease the risk of wait-list mortality, and [give] us the ability to transplant a person sooner,” Humar said in a statement.<\/p>\n
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