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TUESDAY, July 16, 2019 (HealthDay News) — Young adult exposures to elevated systolic and diastolic blood pressure (SBP and DBP) and low-density lipoprotein (LDL) are associated with increased risks for cardiovascular disease (CVD) in later life, according to a study published in the July 23 issue of the Journal of the American College of Cardiology<\/i>.<\/p>\n
Yiyi Zhang, Ph.D., from Columbia University in New York City, and colleagues pooled data from six U.S. cohorts with a total of 36,030 participants to examine independent associations between young adult exposures to risk factors and later-life CVD risk, while accounting for later-life exposures. For every participant, risk factor trajectories were imputed for LDL and high-density lipoprotein cholesterol and SBP and DBP from age 18 years.<\/p>\n
The researchers identified 4,570 coronary heart disease (CHD), 5,119 heart failure, and 2,862 stroke events during a median follow-up of 17 years. Independent of later adult exposures, young adult LDL \u2265100 mg\/dL versus <100 mg\/dL correlated with a 64 percent increased risk for CHD when young and later adult risk factors were considered jointly in the model. Young adult SBP \u2265130 mm Hg versus <120 mm Hg and DBP \u226580 mm Hg versus <80 mm Hg correlated with increased risks for heart failure of 37 and 21 percent, respectively.<\/p>\n
“These findings suggest that investment now in programs to control modifiable risk factors during young adulthood has the potential to reduce the future burden of CVD,” the authors write.<\/p>\n
Abstract\/Full Text<\/a><\/p>\n Editorial (subscription or payment may be required)<\/a><\/p>\n <\/i><\/p>\n