<\/b><\/p>\n
<\/b><\/p>\n
WENDESDAY, June 26, 2019 (HealthDay News) — Micronutrient deficiencies remain common in adults at the time of celiac disease (CD) diagnosis, according to a study published online June 24 in Mayo Clinic Proceedings<\/i>.<\/p>\n
Adam C. Bledsoe, M.D., from the Mayo Clinic in Rochester, Minnesota, and colleagues retrospectively evaluated the frequency of micronutrient deficiencies (tissue transglutaminase IgA, zinc, 25-hydroxy vitamin D [vitamin D], ferritin, albumin, copper, vitamin B12, and serum folate) among 309 adult patients (196 women) with newly diagnosed CD (from Jan. 1, 2000, to Oct. 31, 2014) and compared them to age- and sex-matched controls participating in the National Health and Nutrition Examination Survey.<\/p>\n
The researchers found that only one-quarter of patients had weight loss. Zinc deficiency was more common in CD patients (59.4 percent versus 33.2 percent of controls; P < 0.001), as were deficiencies in albumin (19.7 percent versus 1.1 percent, respectively; P < 0.001), copper (6.4 percent versus 2.1 percent; P = 0.003), vitamin B12 (5.3 percent versus 1.8 percent; P = 0.004), and folate (3.6 percent versus 0.3 percent; P = 0.002). There was no significant difference in vitamin D levels between the groups (19 percent versus 18 percent; P = 0.72). Ferritin was low in 30.8 percent of patients, but no data were available for controls.<\/p>\n
“This study provides support for micronutrient assessment at the time of CD diagnosis,” conclude the authors.<\/p>\n
Two authors reported financial ties to the pharmaceutical industry.<\/p>\n