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TUESDAY, June 4, 2019 (HealthDay News) — For children with eczema, Staphylococcus aureus<\/i> (S. aureus<\/i>) colonization is associated with food sensitization and allergy independent of eczema severity, according to a study published online May 31 in the Journal of Allergy and Clinical Immunology<\/i>.<\/p>\n
Olympia Tsilochristou, M.D., from King’s College London, and colleagues conducted a secondary analysis to examine the correlation of S. aureus<\/i> colonization with specific immunoglobulin E (sIgE) production to common food allergens and allergies in early childhood in relation to eczema severity. In the Learning Early About Peanut Allergy (LEAP) study, eczema severity was assessed and skin\/nasal swabs were cultured for S. aureus<\/i>. sIgE levels were measured to identify sensitization.<\/p>\n
The researchers found that across the LEAP study, there was a significant correlation for skin S. aureus<\/i> colonization with eczema severity; at 12 and 60 months of age, there was a correlation with subsequent eczema deterioration. At any point in time, skin S. aureus<\/i> colonization was associated with elevated levels of hen’s egg white and peanut sIgE, independent of the severity of eczema. At 60 and 72 months of age, participants with S. aureus<\/i> were more likely to have persistent egg allergy and peanut allergy, independent of eczema severity.<\/p>\n
“S. aureus<\/i> has been implicated in the development and severity of atopic diseases, namely eczema, allergic rhinitis, and asthma; our findings extend these observations to the development of food allergy independent of eczema severity,” the authors write.<\/p>\n
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