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TUESDAY, May 21, 2019 (HealthDay News) — Between 1999 and 2016, there were favorable trends in lipid and apolipoprotein B levels in U.S. youth, according to a study published in the May 21 issue of the Journal of the American Medical Association<\/i>.<\/p>\n
Amanda M. Perak, M.D., from the Northwestern University Feinberg School of Medicine in Chicago, and colleagues analyzed trends in levels of lipids and apolipoprotein B in 26,047 U.S. youth aged 6 to 19 years for 1999 through 2016.<\/p>\n
The researchers found that from 1999-2000 to 2015-2016, the adjusted mean total cholesterol level decreased from 164 to 155 mg\/dL among all youth. From 2007-2008 to 2015-2016, the adjusted mean high-density lipoprotein (HDL) cholesterol level increased from 52.5 to 55.0 mg\/dL; the mean non-HDL cholesterol level decreased from 108 to 100 mg\/dL. Geometric mean levels of triglycerides decreased from 78 mg\/dL in 1999-2000 to 63 mg\/dL in 2013-2014 among fasting adolescents; during the same years, the mean levels of low-density lipoprotein cholesterol decreased from 92 to 86 mg\/dL. From 2005-2006 to 2013-2014, the mean levels of apolipoprotein B declined from 70 to 67 mg\/dL. Regarding the prevalence of ideal and adverse levels, favorable trends were generally observed.<\/p>\n
“It will be important to understand the reasons for the favorable lipid trends observed in this study to both acknowledge public health successes and plan future efforts,” the authors write.<\/p>\n
One author disclosed financial ties to NGM Biopharmaceuticals.<\/p>\n
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