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WEDNESDAY, May 8, 2019 (HealthDay News) — Nasal high-frequency oscillatory ventilation (NHFOV) reduces reintubation by more than 50 percent in preterm infants with respiratory distress syndrome (RDS), according to a study published in the April issue of CHEST<\/i>.<\/p>\n
Long Chen, M.D., Ph.D., from Children’s Hospital of Chongqing Medical University in China, and colleagues evaluated whether NHFOV could reduce intubation and partial pressure of carbon dioxide (PCO2<\/sub>) levels versus nasal continuous positive airway pressure (NCPAP) during the postextubation phase in 206 preterm infants (<37 weeks of gestation). The majority of infants (61.7 percent) were diagnosed with RDS, 25.7 percent with acute RDS (ARDS), and 12.6 percent with both.<\/p>\n The researchers found that NHFOV significantly reduced the reintubation rate (16:87 versus 35:68), particularly among infants with a gestational age of \u226432 weeks (12:34 versus 25:20), compared with NCPAP. In the NHFOV group, the PCO2<\/sub> level was also significantly lower than in the NCPAP group. NHFOV significantly reduced the reintubation rate in preterm infants with ARDS (10:33 versus 21:15).<\/p>\n “Usually, one of the most important causes of reintubation is difficulty in clearing the partial pressure of carbon dioxide,” a coauthor said in a statement. “We found that NHFOV was superior to NCPAP in reducing PCO2<\/sub> levels.”<\/p>\n Abstract\/Full Text (subscription or payment may be required)<\/a><\/p>\n <\/i><\/p>\n