Sixteen-week intervention showed significant improvement in Psoriasis Area and Severity Index<\/p>\n<\/h3>\n
By Lori Solomon HealthDay Reporter<\/b>
\n<\/b><\/p>\n
FRIDAY, Sept. 26, 2025 (HealthDay News) — A 16-week Mediterranean diet intervention significantly improves psoriasis severity in patients with mild-to-moderate disease receiving stable topical therapy, according to a study published online Sept. 24 in JAMA Dermatology<\/em>.<\/p>\n Javier Perez-Bootello, M.D., from the Instituto Ram\u00f3n y Cajal de Investigaci\u00f3n Sanitaria in Madrid, and colleagues assessed whether a 16-week Mediterranean diet intervention would improve psoriasis severity in patients with mild-to-moderate disease. The analysis included 37 participants receiving stable topical therapy randomly assigned to a dietitian-guided Mediterranean diet program or standard low-fat dietary advice without dietitian supervision.<\/p>\n The researchers found that the estimated marginal means change in the Psoriasis Area and Severity Index (PASI) at week 16 was \u22123.4 (95 percent confidence interval, \u22124.4 to \u22122.4) in the intervention group and 0.0 (95 percent confidence interval, \u22121.0 to 1.0) in the control group. In the Mediterranean diet group, 47.4 percent achieved a 75 percent reduction in PASI compared with 0 percent in the control group. There was also a significant reduction in glycated hemoglobin in the intervention group versus the control group (between-group estimated marginal means difference, \u22124.1 mmol\/mol; 95 percent confidence interval, \u22126.9 to \u22121.3 mmol\/mol; P\u2009=\u20090.01).<\/p>\n “These findings suggest that incorporating dietary strategies may be beneficial as an adjunctive therapy in psoriasis management,” the authors write.<\/p>\n Abstract\/Full Text (subscription or payment may be required)<\/a><\/p>\n